Search
Skip to Search Results- 2Wu, Nathanael Lap-Yan
- 1Alam, Kazi, MM
- 1Binkhathlan, Ziyad
- 1Epp, Eric
- 1Ginige, Gayashani Kanchana
- 1Jin,Cong
- 4Buriak, Jillian (Chemistry)
- 3Buriak, Jillian M. (Chemistry)
- 2Brett, Michael J. (Electrical and Computer Engineering)
- 2Choi, Phillip (Chemical and Materials Engineering)
- 2Lavasanifar, Afsaneh (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Brocks, Dion R. (Faculty of Pharmacy and Pharmaceutical Sciences)
-
(RADA)4 Self-Assembling Peptide based Hydrogels: Design, Characterization and In-Vitro Biological Evaluation
DownloadFall 2016
Ionic self-assembling peptides have emerged as promising nano-biomaterials, with direct applications in the fields of bioengineering and applicative medicine. (RADA)4 is a self-assembling 16 residue containing peptide, with alternating hydrophobic and hydrophilic residues. This characteristic...
-
Fall 2015
2015 marks the 50th anniversary of Moore's law, which has described the exponential progress in semiconductor patterning technologies, enabling creation of smaller circuitry features at greater densities. These continued hardware developments, economically mass manufactured, have made possible...
-
Fall 2014
Rosette Nanotubes (RNTs) are a class of self-assembled organic nanomaterials generated through the spontaneous hierarchical organization of guanine-cytosine (G˄C) bases with a built-in self-assembling ability. Driven by non-covalent intermolecular forces in solution, G˄C bases self-assemble into...
-
Fall 2017
The development of photolithography has been the main driving force of the semiconductor industry to keep pace with Moore’s Law for over five decades. The theoretical resolution limit of state-of-the-art 193 nm photolithography is about 36 nm (half pitch). By integrating multiple patterning...
-
Spring 2022
Molecular self-assembly is the basis of structure in Nature. While of far less complexity than a natural system, the same physical rules apply to simple synthetic designed systems that spontaneously form self-assembled structures and patterns. The self-assembly of block copolymers (BCPs) is an...
-
Design and synthesis of renewable lipid-based nanocarriers with thermosensitivity for targeted drug delivery applications
DownloadSpring 2024
Numerous drug molecules currently available on the market suffer from short half-life, in vivo instability, poor bioavailability, rapid degradation and inappropriate distribution. While nanocarriers have emerged as a promising solution to address these issues, the primary objective and challenge...
-
Design of Macromolecular Anti-cancer Drug Delivery Systems using Molecular Dynamics Simulation
DownloadFall 2015
In recent years, the application of self-associating block copolymer based drug delivery systems has attracted increasing attention as nano-sized carriers for the encapsulation and the controlled delivery of water insoluble drugs. Most of the drug formulations are based on the “trial and error”...
-
Spring 2010
In recent years, the use of self-associating block copolymer based drug delivery systems have attracted increasing attention as nanoscopic carriers for the encapsulation and the controlled delivery of water insoluble drugs. Currently, most of the drug formulations proceed by “trial and error”...
-
Development of block copolymer based nanocarriers for the solubilization and delivery of valspodar
DownloadFall 2011
One of the major causes of failure in cancer chemotherapy is multidrug resistance (MDR), where cancer cells become resistant to different types of anticancer drugs. Over-expression of membrane efflux pumps like P-glycoprotein (P-gp), which recognizes different chemotherapeutic agents and...
-
Spring 2010
Nanoscale patterning of organic molecules has received considerable attention in current nanoscience for a broad range of technological applications. In order to provide a viable approach, this thesis describes catalytic stamp lithography, a novel soft-lithographic process that can easily...