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Spring 2013

Toman, John T

Electrografting permits bonding of an organic film to a conductive substrate. It is therefore important to control the formation of organic films as best as possible and to understand the linkage between the organic film and the substrate as best as possible. This work explores electrografting of...

2018-01-01

Zhang, Wei, Wei, Menglian, Carvalho, Wildemar S. P., Serpe, Michael J.

A biosensor for mouse Immunoglobulin G (IgG) was generated from responsive polymer-based interference filters (etalons). To accomplish this, an excess amount of alkaline phosphatase-modified goat anti-mouse IgG (AP-GAM, F(ab’)2 fragment specific to mouse IgG) was added to mouse IgG, and allowed...

Spring 2014

Peters, Robert F

Biosensing involves the detection of analytes using biological elements as receptor agents for the specific binding of molecules to a surface. Surface-enhanced Raman spectroscopy (SERS), a surface-sensitive vibrational spectroscopy technique used to amplify Raman signals, provides unique...

2013-01-01

Islam, Molla R., Serpe, Michael J.

Dual pH and temperature sensitive microgel-based etalons were fabricated by sandwiching a “monolithic” microgel layer between two semitransparent, Au layers. The devices exhibit visual color and multipeak reflectance spectra, both of which primarily depend on the distance between the Au surfaces...

Fall 2010

Gish, Douglas

This research investigates an extension of the glancing angle deposition (GLAD) technique and a biosensing application of films produced by GLAD. The extension to GLAD, called phi-sweep (PS), improves column isolation compared to films grown by traditional GLAD (TG) as well as modifies the column...

2013-01-01

Islam, Molla R., Lu, Zhenzhen, Li, Xue, Sarker, Avijeet K., Hu, Liang, Choi, Paul, Li, Xi, Hakobyan, Narek, Serpe, Michael J.

Stimuli-responsive polymers are capable of translating changes in their local environment to changes in their chemical and/or physical properties. This ability allows stimuli-responsive polymers to be used for a wide range of applications. In this review, we highlight the analytical applications...

Spring 2018

Cao, Yong

Small-molecule metabolites (MW < 1,000 Da) are now emerging as an important type of biomarkers, thanks to the rapid development of systems biology such as metabolomics. Compared to nucleic acids and protein, metabolite is closer to the phenotype. Rapid detection and quantification of metabolites...