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Skip to Search Results- 3Department of Agricultural, Food, and Nutritional Science
- 3Department of Chemical and Materials Engineering
- 2Faculty of Pharmacy and Pharmaceutical Sciences
- 2Medical Sciences-Laboratory Medicine and Pathology
- 1Department of Agricultural, Food and Nutritional Science
- 1Department of Chemistry
- 1Ball, Ron (Agricultural, Food and Nutritional Science)
- 1Betti, Mirko
- 1Catherine B. Chan (Agricultural, Food and Nutritional Science)
- 1Chen, Lingyun (Agricultural, Food and Nutritional Science)
- 1Dr. Afsaneh Lavasanifar (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Jamali, Fakhreddin (Pharmaceutical Sciences)
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Fall 2012
Glucosamine (GlcN) is an amino monosaccharide that is widely used as a food supplement in the treatment of osteoarthritis (OA). In vitro and animal studies strongly support the therapeutic efficacy of the compound; however, clinical reports and meta-analysis are inconclusive. As compared to the...
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Spring 2011
The objective of this thesis is to design nanoparticle (NP)-based drug delivery systems suitable for treatment of bone diseases. Two types of nanocarriers, (1) polymer coated bovine serum albumin (BSA) NPs and (2) lipid based NPs (micelles and liposomes) were investigated. The BSA NPs were...
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Cell-electronic Sensing of Cellular Responses and Toxicity Induced by Nanoparticles and Arsenic Species
DownloadFall 2013
We demonstrate the development of a real-time cell analysis (RTCA) platform for studying nanoparticle- and arsenic-induced cytotoxicity with potential applications to risk assessment, environmental toxicity monitoring, and drug development. RTCA is an impedance-based in vitro detection system...
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Evaluation of the threonine requirement and the bioavailability of threonine in feedstuffs in pregnant sows
DownloadFall 2010
Current recommendations for amino acid intake during pregnancy are for a constant amino acid intake throughout. However, the demand for amino acids changes from maternal tissue growth in early gestation to fetal, conceptus and mammary tissue development in late gestation. The availability of...
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Spring 2018
Collagen hydrolysates (CH) are emerging health supplements associated with a growing body of evidence indicating that they may positively influence skin conditions, promote joint and bone health, and even ameliorate hypertension and type 2 diabetes. The biological effects of CH, however, are...
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Intestinal Uptake of Barley Protein Nanoparticles as Delivery Vehicles for Bioactive Compounds
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The use of nanoparticles as nutrient delivery vehicles enables the enhancement of the oral bioavailability and health promoting benefits of bioactive compounds. Barley protein nanoparticles were developed in previous study for hydrophobic compound delivery. The objective of the present study was...
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Nanodelivery of Novel Inhibitors of ERCC1/XPF for sensitizing colorectal cancer cell to platinum drugs
DownloadSpring 2023
This project's long-term goal is to increase the efficacy of genotoxic therapeutics through thesensitization of cells to DNA-damaging therapy ahead of the treatment. The focus of this projectwas on the enhancement of platinum-based chemotherapeutics in colorectal cancer usingcolorectal cancer...
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Spring 2012
The present thesis describes preliminary studies required for evaluating silicon nanocrystals (Si-NCs) as photothermal (PT) therapy agents and drug delivery vehicles. Group 14 semiconductor NCs are of particular interest for these applications because of their tailorable optical response and...
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Proanthocyanidins and Glucose Homeostasis: An Analysis of Bioavailability and Mechanisms in Rats
DownloadFall 2015
Proanthocyanidins (PAC) belong to a highly consumed class of flavonoids and their consumption has been linked to beneficial effects on glycemic control in type 2 diabetes. However, limited gastrointestinal absorption occurs due to the structure complexity of polymeric PAC and the mechanisms by...