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Skip to Search Results- 75Graduate and Postdoctoral Studies (GPS), Faculty of
- 75Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 12School of Public Health
- 11Nursing, Faculty of
- 10School of Public Health/Journal Articles (Public Health)
- 6Biological Sciences, Department of
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2009-05-28
Fergenbaum, Jennifer H., Bruce, Sharon, Lou, Wendy, Hanley, Anthony J.G., Greenwood, Carol, Young, T. Kue
"The association between obesity, other cardiovascular risk factors, and cognitive function in a Canadian First Nations population was investigated using a cross‐sectional design. Eligible individuals were aged ≥18 years, without a history of stroke, nonpregnant, with First Nations status, and...
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Fall 2009
The analysis of wide-angle cellular light scattering patterns is a challenging problem. Small changes to the organization, orientation, shape, and optical properties of scatterers and scattering populations can significantly alter their complex two-dimensional scattering signatures. Because of...
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Fall 2009
There is substantial evidence of the elevated risk of cancer among individuals with type 2 diabetes. Very little is known, however, about the role that antidiabetic therapies play in this relationship. The objective of this program of research was to examine whether there is a therapeutic risk...
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2009
Svenson, L. W., Schopflocher, D. P., Yiannakoulias, N.
Background Geographic public health surveillance is concerned with describing and disseminating geographic information about disease and other measures of health to policy makers and the public. While methodological developments in the geographical analysis of disease are numerous, few have been...
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Delivery of STAT3 inhibitor cucurbitacins to tumor by polymeric nano-carriers : Implications in cancer chemo- and immunotherapy
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Signal Transducer and Activator of Transcription 3 (STAT3), a common oncogenic mediator, is constitutively activated in many types of human cancers and plays a critical role in tumor growth and cancer immune evasion. The focus of this dissertation is the delivery of STAT3 inhibitor cucurbitacins...
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Outcomes of antiretroviral therapy in northern Alberta: the impact of Aboriginal ethnicity and injection drug use
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Background: Aboriginals are overrepresented in Canada’s HIV epidemic and are more likely to be infected with HIV through injection drug use (IDU) than non-Aboriginals. However, little research has investigated the outcomes of combination antiretroviral therapy (cART) among Aboriginal...
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The relationship between body mass index, treatment, and mortality in patients with established coronary artery disease:a report from APPROACH.
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Padwal, R. A., Sharma, A., Kalanta-Zadeh, K., Oreopoulos, A., Norris, C.M., McAlister, F. A., Ezekowitz, J., Fonarow, G.C.
Our objective was to examine the association between body mass index (BMI) and survival according to the type of treatment in individuals with established coronary artery disease (CAD). Methods and results: Patients with CAD were identified in the Alberta Provincial Project for Outcome Assessment...
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Food intake behaviour in advanced cancer – implications of taste and smell alterations, orosensory reward, and cannabinoid therapy
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Food intake is regulated by both appetite and orosensory reward systems. Appetite systems stimulate or reduce hunger, while orosensory reward motivates consumption of high fat sweet foods, resulting in food enjoyment. The majority of advanced cancer patients suffer from malnutrition and wasting,...
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Application of ROC curve analysis to metabolomics data sets for the detection of cancer in a mouse model
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The goal of this study was to show that quantifiable metabolic changes may be used to screen for cancer. NIH III nude mice (n=22) were injected with human GBM cells, with daily urine samples collected pre and post-injection. 14 mice were injected with saline to serve as controls. The...
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Fall 2010
In many tumors, persistently-active signal transducer and activator of transcription 3 (STAT3) imparts several oncogenic features such as survival, proliferation, angiogenesis, and immune escape. Therefore, STAT3 targeting in cancer and cancer-exposed dendritic cells (DCs) is important for cancer...