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Skip to Search Results- 1Begam, Rowshon A
- 1Cochrane, Rachel V K
- 1De Agostini Verna, Carla
- 1Gao, Zhizeng
- 1Gardiner, Jason L
- 1Johnson, Bradley Neil.
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Biochemical investigations of two polyketide synthase subclasses – highly reducing/non-reducing pairs, and polyketide synthase non-ribosomal peptide synthetases.
DownloadSpring 2016
Cladosporin is a polyketide metabolite that is biosynthesized by a highly reducing (HR)/non-reducing (NR) polyketide synthase (PKS) pair, wherein they catalyse head-totail condensation of acetyl and malonyl CoA units with subsequent β-keto modification. Cladosporin has recently been reported as a...
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Biosynthetic Studies of Resorcylic Acid Lactones, Hypothemycin, Radicicol, and Dehydrocurvularin
DownloadFall 2013
Fungal polyketides, a vast source for pharmaceutical industries, are biosynthesized by multifunctional iterative polyketide synthases (PKS). The biosynthesis employs complex programming rules, which are currently unresolved. To decode the programming rules, the biosynthesis of three polyketides,...
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Fall 2014
Most multicellular organisms form tissue networks for transport function. What controls the formation of tissue networks is thus a central question in biology. In animals, the formation of these networks often involves extensive cell movements—movements that are instead prevented in plants by a...
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Fall 2018
Vascular networks transport water, signals and nutrients in both plants and animals; what controls the formation of these networks is thus a central question in biology. In animals, vascular network formation requires direct cell-cell communication and often cell movements, both of which are...
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Fall 2022
To form tissue networks, animal cells migrate and interact through proteins protruding from their plasma membranes. Plant cells can do neither, yet plants form vein networks. How plants do so is unclear, but the prevailing hypothesis proposes that GNOM — a regulator of vesicle formation in...
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Exploring the role of the thioredoxin system, peroxiredoxins and glutaredoxins in aluminum and cadmium tolerance in yeast and Arabidopsis thaliana
DownloadFall 2011
Aluminum (Al) and cadmium (Cd) are non-redox active metal ions of agricultural importance. Both are able to induce oxidative damage as a mechanism of toxicity. To increase our understanding of the mechanisms of Al and Cd toxicity and tolerance in plants, the potential role of antioxidant enzymes...
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Expression and purification of recombinant forms of two Arabidopsis thaliana PR-10 homologues (MLP423 and Bet v 1)
DownloadFall 2013
Pathogenesis related 10 (PR-10) proteins have important roles in mediating plant abiotic and biotic stress tolerance. Most of the members of this family possess ribonuclease activity. The homologues of PR-10 (ABR17) protein, MLP423 and Bet v 1, may have similar biological and physiological...