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Skip to Search Results- 52Graduate and Postdoctoral Studies (GPS), Faculty of
- 52Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 10Agricultural, Food and Nutritional Science, Department of
- 10Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 10Nursing, Faculty of
- 5Nursing, Faculty of/Chronicity
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Reducing depression in older home care clients: Design of a prospective study of a nurse-led interprofessional mental health promotion intervention
Download2011
Gibson, M., Markle-Reid, M., Thabane, L., Pierce, T., Hoch, J., McAiney, C., Busing, B., Browne, G., Forbes, D.
Background: Very little research has been conducted in the area of depression among older home care clients using personal support services. These older adults are particularly vulnerable to depression because of decreased cognition, comorbid chronic conditions, functional limitations, lack of...
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Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphate
Download2015
Zhao, Yuan Y., McMullen,Todd P. W. , Brindley, David N., Curtis, Jonathan M., Benesch, Matthew G. K.
Autotaxin (ATX) is a secreted enzyme, which produces extracellular lysophosphatidate (LPA) from lysophosphatidylcholine (LPC). LPA activates six G protein-coupled receptors and this is essential for vasculogenesis during embryonic development. ATX is also involved in wound healing and...
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Fall 2020
Infectious respiratory diseases, caused by viruses and bacteria that attack the respiratory system, constitute a serious threat in public health around the world. Pathogens can be transmitted in the air though large droplets or aerosols. As aerosols can linger in the environment for a prolonged...
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2012
Cutler, J. E., Dziadek, S., Bundle, D. R., Cartmell, J., Xin, H., Bailey, J. J.
Our research on pathogenesis of disseminated candidiasis led to the discovery that antibodies specific for Candida albicans cell surface b-1, 2–mannotriose [b-(Man)3] protect mice. A 14 mer peptide Fba, which derived from the N-terminal portion of the C. albicans cytosolic/cell surface protein...
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Small intestine early innate immunity response during intestinal colonization by Escherichia coli depends on its extra-intestinal virulence status
Download2016
Denamur, Erick, Tourret, Jérôme, Dion, Sara, Willing, Benjamin P., Wachtel, Sarah, Finlay, B. Brett, Dufour, Nicolas, Croxen, Matthew A.
Uropathogenic Escherichia coli (UPEC) strains live as commensals in the digestive tract of the host, but they can also initiate urinary tract infections. The aim of this work was to determine how a host detects the presence of a new UPEC strain in the digestive tract. Mice were orally challenged...
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Structural changes of the amygdala subnuclei and limbic white matter tracts in healthy aging and major depressive disorder
DownloadFall 2019
The world population is dramatically aging. Several factors affect brain in healthy aging. The apolipoprotein E (APOE), brain-derived neurotrophic factor (BDNF) and catechol-O-methyl transferase (COMT) might be involved in neurodegenerative diseases, depression and cognitive decline in healthy...
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Structure-Affinity Relationship Study of Novel Imidazoline Ligands at Imidazoline Binding Sites and α-Adrenoceptors
DownloadFall 2014
Many drugs containing an imidazoline moiety are thought to bind to both imidazoline binding sites (IBS) and α-adrenoceptors (α-AR) to mediate their therapeutic effects. To aid in better characterisation of these binding sites, the structure-affinity relationships of several new series of...
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Spring 2024
Mental disorders are one of the leading health problems affecting Canadian children and youth. Teachers are considered frontline workers in child mental health due to the amount of time children spend at school. Given the high prevalence of mental disorders, and the amount of time teachers spend...