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Skip to Search Results- 1Adam, Ibrahim S. Y.
- 1Beltaos, Angela M
- 1Chow, Aaron K.Y.
- 1Davis, Matthew, B
- 1Dickau, Matthew A
- 1Erland, Broghan
- 5Department of Mechanical Engineering
- 2Department of Chemistry
- 1Department of Agricultural, Food and Nutritional Science
- 1Department of Civil and Environmental Engineering
- 1Department of Earth and Atmospheric Sciences
- 1Department of Electrical and Computer Engineering
- 3Olfert, Jason (Mechanical Engineering)
- 1Bergren, Adam (National Institute for Nanotechnology)
- 1Bressler, David (Department of Agricultural, Food and Nutritional Science)
- 1Checkel, M. David (Mechanical Engineering
- 1Gamon, John (Earth and Atmospheric Sciences, Biological Sciences
- 1Gina R. Rayat (Surgery)
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A novel mouse model of acute antibody-mediated transplant rejection shows simultaneous complement activating and anti-inflammatory effects of donor specific IgG antibodies
DownloadFall 2013
We developed a small animal model of pure antibody-mediated rejection (ABMR) by utilizing fully major histocompatibility complex (MHC) mismatched kidney allografts in mice. By examining resultant ABMR pathology, we show that terminal complement products C5a and C5b-9 are crucial in establishing...
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Fall 2020
Introduction: ABO-incompatible organ transplants (ABOi-Tx) recipients are at high-risk of rapid rejection mediated by ABO antibodies (ABO Abs). To manage and expand ABOi-Tx, it is necessary to understand the mechanism(s) by which natural and induced ABO Abs develop. Prior studies have used...
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Fall 2014
Carbohydrate–protein interactions play key roles in a range of biological processes. Noticeable advancements have been made in understanding the features associated with the recognition of pyranosides (six-membered ring sugars) by proteins. In contrast, similar detailed studies about the...
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Boxed-in: Comparing Algorithms for Box-flight Mass-Balance Greenhouse Gas Flux Measurements from Mineable and In Situ Oil Sands Developments
DownloadSpring 2022
To combat global warming, Canada has committed to reducing greenhouse gases (GHGs) 40-45% below 2005 emission levels by 2025. Monitoring emissions and deriving accurate inventories are essential to reaching these goals. GHGs can be measured at a small scale, often using ground measurements which...
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Development and Applications of an Emissions Micro-Simulation Tool for Transportation Infrastructure Design
DownloadFall 2014
Transportation emissions constitute a significant portion of overall emissions inventories, and contribute to air quality health concerns. Reductions in transportation emissions can be achieved through efficient design of infrastructure, effective policy and regulation, and informed planning...
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Spring 2014
The development of rapid detection techniques to be applied at the point of use, has been gaining significant attention in the recent years. Rapid techniques are important and preferable methods in healthcare and environment sector due to the advantages they offer such as low-cost and reduced...
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Fall 2022
Background: Although pediatric heart transplantation is a life-saving and effective therapy for children with cardiac disease, barriers remain due to a lack of available organs as well as transplant failure due to rejection. This dissertation aimed to increase knowledge related to immune risk...
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Implementation and Evaluation of Spatiotemporal Prediction Algorithms and Prediction of Spatially Distributed Greenhouse Gas Inventories
DownloadFall 2011
Growing environmental concerns require monitoring and modelling of greenhouse gases. These modelling efforts require processing of massive datasets in a timely fashion. This, in turn, can lead to feasibility problems when estimating values of missing data points. This thesis examines and compares...
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Improving Measurements of the Mixing State and Mass Concentration of Particulate Emissions from Aircraft Engines
DownloadSpring 2016
This research is focused towards improving techniques used to measure particulate emissions from aircraft engines, on two fronts: first, to characterize and quantify the mixing state of particulate emissions; and second, to calibrate black carbon mass instruments with a traceable mass...
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Fall 2009
Islet transplantation has the potential to be an effective treatment for patients with type 1 diabetes. However, a shortage of human donor islets and the need for continuous immunosuppressive therapy currently limit this therapy to patients with brittle type 1 diabetes. Neonatal pigs may...