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Skip to Search Results- 1Adam, Ibrahim S. Y.
- 1Aguda, R. M.
- 1Bergeron, Amber
- 1Bottrell, D. G.
- 1Brachmann, Cole Garrett
- 1Chow, Aaron K.Y.
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A novel mouse model of acute antibody-mediated transplant rejection shows simultaneous complement activating and anti-inflammatory effects of donor specific IgG antibodies
DownloadFall 2013
We developed a small animal model of pure antibody-mediated rejection (ABMR) by utilizing fully major histocompatibility complex (MHC) mismatched kidney allografts in mice. By examining resultant ABMR pathology, we show that terminal complement products C5a and C5b-9 are crucial in establishing...
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Fall 2020
Introduction: ABO-incompatible organ transplants (ABOi-Tx) recipients are at high-risk of rapid rejection mediated by ABO antibodies (ABO Abs). To manage and expand ABOi-Tx, it is necessary to understand the mechanism(s) by which natural and induced ABO Abs develop. Prior studies have used...
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Spring 2015
Background: Heart transplant is life-saving for children with end-stage congenital heart disease or acquired heart failure. Critical illness following transplantation can include acute kidney injury (AKI). There is little data on the epidemiology of, risk factors for, or impact on outcomes of...
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An examination of linking and blocking procedures for use in deflection cantilever array-based protein detection
DownloadFall 2011
In this project common linking and blocking procedures were examined for use in multiplexed deflection cantilever array-based detection of proteins. A human interferon gamma (INF-γ) enzyme-linked immunosorbent assay (ELISA) kit was used to evaluate the effectiveness of the linking and blocking...
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Fall 2014
Carbohydrate–protein interactions play key roles in a range of biological processes. Noticeable advancements have been made in understanding the features associated with the recognition of pyranosides (six-membered ring sugars) by proteins. In contrast, similar detailed studies about the...
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Bacillus thuringiensis isolates from the Philippines: habitat distribution, delta-endotoxin diversity, and toxicity to rice stem borers (Lepidoptera: Pyralidae)
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Cohen, M. B., Aguda, R. M., Bottrell, D. G., Gould, F. L., Litsinger, J. A., Theunis, W., Peferoen, M., Cruz, W. T., Decock, C., Lambert, B.
Abstract: Bacillus thuringiensis Berliner isolates were detected in 57% of 801 samples of rice grain dust, soil, rice field arthropods, and miscellaneous habitats (rice straw compost and mammal faeces) collected at 100 sites in the Philippines. The collection yielded 3950 isolates of B....
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Fall 2011
High aspect ratio microelectromechanical structures have been found, in the literature, to collapse due to capillary forces of liquids. In this dissertation, mathematical models are developed to study (i) the collapse of a microstructure represented by a double cantilevered beam (DCB) with a free...
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Characteristics of alpine plants and soils along an elevational gradient, Northern Selkirk Mountains, British Columbia
DownloadSpring 2019
Rates of climate change are accelerated at higher elevations, a pattern termed elevation-dependent warming (EDW). Consequently, the impacts of climate change on community patterning and soil development may be particularly evident in alpine environments. Alpine ecotone boundaries, such as...
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Spring 2014
The development of rapid detection techniques to be applied at the point of use, has been gaining significant attention in the recent years. Rapid techniques are important and preferable methods in healthcare and environment sector due to the advantages they offer such as low-cost and reduced...
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Estimating the Seroprevalence of Cytomegalovirus (CMV), Epstein-Barr Virus (EBV) and the Risk of Transfusion-Transmitted and Community-Acquired CMV Infection in Solid Organ Transplant Donors and Recipients
DownloadFall 2019
Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) are ubiquitous herpesviruses that establish lifelong, often asymptomatic, infections in healthy people, but are responsible for significant morbidity and mortality in certain hosts. CMV is the most common congenital infection worldwide, causing...