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Skip to Search Results- 6Kitova, Elena N.
- 6Klassen, John S.
- 2Cairo, Christopher W.
- 2Darestani, Reza R.
- 2Eugenio, Luiz
- 2Fan, Xuxin
- 9Graduate and Postdoctoral Studies (GPS), Faculty of
- 9Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 8Chemistry, Department of
- 8Chemistry, Department of/Journal Articles (Chemistry)
- 5Biological Sciences, Department of
- 5Biological Sciences, Department of/Journal Articles (Biological Sciences)
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A novel mouse model of acute antibody-mediated transplant rejection shows simultaneous complement activating and anti-inflammatory effects of donor specific IgG antibodies
DownloadFall 2013
We developed a small animal model of pure antibody-mediated rejection (ABMR) by utilizing fully major histocompatibility complex (MHC) mismatched kidney allografts in mice. By examining resultant ABMR pathology, we show that terminal complement products C5a and C5b-9 are crucial in establishing...
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Fall 2020
Introduction: ABO-incompatible organ transplants (ABOi-Tx) recipients are at high-risk of rapid rejection mediated by ABO antibodies (ABO Abs). To manage and expand ABOi-Tx, it is necessary to understand the mechanism(s) by which natural and induced ABO Abs develop. Prior studies have used...
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1994
Wright, G.E., Reha-Krantz, L.J., Khan, N.N.
Bacteriophage T4 DNA polymerase was Inhibited by butylphenyl nucleotldes, aphldlcolin and pyrophosphate analogs, but with lower sensitivities than other members of the B family DNA polymerases. The nucleotides N2-{p-n-butylphenyl)dGTP (BuPdGTP) and 2-{p-n-butylanilino)dATP (BuAdATP) inhibited T4...
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Fall 2014
Carbohydrate–protein interactions play key roles in a range of biological processes. Noticeable advancements have been made in understanding the features associated with the recognition of pyranosides (six-membered ring sugars) by proteins. In contrast, similar detailed studies about the...
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Bacillus thuringiensis isolates from the Philippines: habitat distribution, delta-endotoxin diversity, and toxicity to rice stem borers (Lepidoptera: Pyralidae)
Download1998
Cohen, M. B., Aguda, R. M., Bottrell, D. G., Gould, F. L., Litsinger, J. A., Theunis, W., Peferoen, M., Cruz, W. T., Decock, C., Lambert, B.
Abstract: Bacillus thuringiensis Berliner isolates were detected in 57% of 801 samples of rice grain dust, soil, rice field arthropods, and miscellaneous habitats (rice straw compost and mammal faeces) collected at 100 sites in the Philippines. The collection yielded 3950 isolates of B....
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Spring 2014
The development of rapid detection techniques to be applied at the point of use, has been gaining significant attention in the recent years. Rapid techniques are important and preferable methods in healthcare and environment sector due to the advantages they offer such as low-cost and reduced...
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E.coli and bacteriophage T4: Using lytic bacteriophages to prevent tissue culture contamination
Download2014-07-04
Bacteria are commonly encountered cell culture contaminants. Due to the costly consequences of media contamination and the loss of research production, further research should be devoted to the prevention of contamination so time and money are not wasted. Phage have been demonstrated to prevent...
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Gene structure of the goldfish agouti-signaling protein: A putative role in the dorsal-ventral pigment pattern of fish
Download2005
Schioth, H.B., Haitina, T., Cerdá-Reverter, J.M., Peter, R.E.
One of the most successful chromatic adaptations in vertebrates is the dorsal-ventral pigment pattern in which the dorsal skin is darkly colored, whereas the ventrum is light. In fish, the latter pattern is achieved because a melanization inhibition factor inhibits melanoblast differentiation and...
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2007
Wang, W., Wang, H., Wong, G.K.S., Zheng, H., Clark, T., Zhang, G., Kang, L., Wang, J., Shi, J., Wang, X.
Background Insects constitute the vast majority of known species with their importance including biodiversity, agricultural, and human health concerns. It is likely that the successful adaptation of the Insecta clade depends on specific components in its proteome that give rise to specialized...
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Fall 2022
Background: Although pediatric heart transplantation is a life-saving and effective therapy for children with cardiac disease, barriers remain due to a lack of available organs as well as transplant failure due to rejection. This dissertation aimed to increase knowledge related to immune risk...