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Fall 2017
Density-based clustering methods extract high density clusters which are separated by regions of lower density. HDBSCAN* is an existing algorithm for producing a density-based cluster hierarchy. To obtain clusters from this hierarchy it includes an instance of FOSC(Framework for Optimal Selection...
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Fall 2018
Identifying the peptide sequence from a mass spectrum is done either by database search or De novo peptide sequencing. This thesis focuses on identification of peptides by using database search, which is a process where an MS/MS spectrum is searched against an entire database of spectra...
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Fall 2014
We address the problem of finding ‘surprising’ patterns of variable length in sequence data, where a surprising pattern is defined as a subsequence of a longer sequence, whose observed frequency is statistically significant with respect to a given distribution.Finding statistically significant...