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Fall 2016
Apolipoprotein E (APOE) ɛ4 and Clusterin (CLU) C alleles are risk factors for Alzheimer’s disease (AD) and preclinical cognitive and memory decline in older adults. We investigated whether memory resilience to genetic risk (i.e., Apolipoprotein E [APOE] ɛ4, Clusterin [CLU] CC, and a high additive...
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Synergistic Associations of Genetic, Demographic, Health, and Lifestyle Risk Factors on Neurocognitive Performance and Change in Aging
DownloadSpring 2016
Objective: Neurocognitive phenotypes observed in aging have been linked to select combinations of candidate genetic polymorphisms and modifiable risk factors. In this dissertation, I test multiple methods and approaches to examine three modifiable risk domains (i.e., demographic, health,...
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