Journal Articles (Agricultural, Food and Nutritional Science)

2016

Ladinig, Andrea, Stothard, Paul, Bao, Hua, Hong, Linjun, Lunney, Joan K., Harding, John C. S., Wilkinson, Jamie M., Plastow, Graham S.

Background Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection of pregnant pigs can result in congenital infection and ultimately fetal death. Little is known about immune responses to infection at the maternal-fetal interface and in the fetus itself, or the molecular events...

2015

Ekine-Dzivenu, Chinyere, Basarab, John A., Li, Changxi, Chen, Liuhong, Vinsky, Michael D., Aalhus, Jennifer L., Fitzsimmons, Carolyn J., Stothard, Paul, Dugan, Mike E. R.

Background Identification of genetic variants that are associated with fatty acid composition in beef will enhance our understanding of host genetic influence on the trait and also allow for more effective improvement of beef fatty acid profiles through genomic selection and marker-assisted diet...

2016

Nayeri, Shadi, Stothard, Paul, Moore, Stephen S., Abo-Ismail, Mohammed K., May, Natalie, Schenkel, Flavio, Sargolzaei, Mehdi, Miller, Stephen P.

Background Genome-wide association studies (GWAS) are a powerful tool for detecting genomic regions explaining variation in phenotype. The objectives of the present study were to identify or refine the positions of genomic regions affecting milk production, milk components and fertility traits in...

2015

Hu, Zhiqiu, Yang, Rong-Cai, Peng, Fred Y.

Early flowering is an important trait influencing grain yield and quality in wheat (Triticum aestivum L.) and barley (Hordeum vulgare L.) in short-season cropping regions. However, due to large and complex genomes of these species, direct identification of flowering genes and their molecular...

2010

Dennis, Jonathan J., Stothard, Paul, Lynch, Karlene H.

Background The Burkholderia cepacia complex (BCC) is comprised of at least seventeen Gram-negative species that cause infections in cystic fibrosis patients. Because BCC bacteria are broadly antibiotic resistant, phage therapy is currently being investigated as a possible alternative treatment...

2005

Chan, Catherine B., Wheeler, Michael B., Asghar, Zeenat, Diao, Jingyu

The insulin receptor (IR) and its signaling appear to be essential for insulin secretion from pancreatic β-cells. However, much less is known about the role of the IR in α-cells. To assess the role of the IR in glucagon and insulin secretion, we engineered adeno-viruses for high efficiency small...

2011

Johnson, Ian R., Ewaschuk, Julia B., Murdoch, Gordon K., Field, Catherine J., Madsen, Karen L.

The weaning period is associated with an increased prevalence of gastrointestinal infection in many species. Glutamine (Gln) has been shown to improve intestinal barrier function and immune function in both in vivo and in vitro models. The objective of the present study was to determine the...

2014-01-01

Teixeira, Januana S., Seeras, Arisha, Sanchez-Maldonado, Alma Fernanda, Zhang, Chonggang, Su, Marcia Shu-Wei, Gänzle, Michael G.

This study aimed to determine whether glutamine deamidation improves acid resistance of Lactobacillus reuteri, and to assess whether arginine, glutamine, and glutamate-mediated acid resistance are redundant or complementary mechanisms of acid resistance. Three putative glutaminase genes, gls1,...

2015

Moore, Stephen S., Miller, Joshua M., Coltman, David W., Liao, Xiaoping, Stothard, Paul

Background Whole genome sequences (WGS) have proliferated as sequencing technology continues to improve and costs decline. While many WGS of model or domestic organisms have been produced, a growing number of non-model species are also being sequenced. In the absence of a reference, construction...

2015

Nimalaratne, Chamila, Wu, Jianping

Intake of antioxidants through diet is known to be important in reducing oxidative damage in cells and improving human health. Although eggs are known for their exceptional, nutritional quality, they are not generally considered as antioxidant foods. This review aims to establish the importance...