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Journal Articles (Agricultural, Food and Nutritional Science)
Items in this Collection
- 1Barnes, Peter J.
- 1Curtis, Jonathan M.
- 1Ito, Kazuhiro
- 1Kimura, Genki
- 1Kizawa, Yasuo
- 1Mercado, Nicolas
- 1Antioxidants
- 1Chronic Obstructive Pulmonary Disease
- 1Dimers (Chemical Physics)
- 1Immunoblotting
- 1Kinase Inhibitors
- 1Oxidative Stress
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Activation of transcription factor Nrf2 signalling by the sphingosine kinase inhibitor SKI-II is mediated by the formation of Keap1 dimers
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Ueda, Keitaro, Ito, Kazuhiro, Kimura, Genki, Moses, Audric, Xiong, Yeping, Kizawa, Yasuo, Curtis, Jonathan M., Barnes, Peter J., Mercado, Nicolas
Anti-oxidant capacity is crucial defence against environmental or endogenous oxidative stress. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a redox-sensitive transcription factor that plays a key defensive role against oxidative and cytotoxic stress and cellular senescence. However, Nrf2...