Journal Articles (Pharmacy and Pharmaceutical Sciences)
Items in this Collection
- 10Löbenberg, Raimar
- 6Azarmi, Shirzad
- 6Löbenberg, R.
- 5Roa, Wilson H.
- 3Finlay, W. H.
- 3Finlay, Warren H.
-
1996
Abstract: Macrophages play an important role in the immunopathogenesis of AIDS, The objective of this study was to investigate the possibility of specific targeting of antivirals such as azidothymidine (AZT) to macrophages, using nanoparticles as a colloidal drug carrier, The body distribution of...
-
Metabolism of isoniazid by neutrophil myeloperoxidase leads to isoniazid-NAD+ adduct formation: A comparison of the reactivity of isoniazid with its known human metabolites
Download2024-01-01
The formation of isonicotinyl-nicotinamide adenine dinucleotide (INH-NAD+) via the mycobacterial catalase-peroxidase enzyme, katG, has been described as the major component of the mode of action of isoniazid (INH). However, there are numerous of human peroxidases that may catalyze this reaction....
-
Optimization of a two-step desolvation method for preparing gelatin nanoparticles and cell uptake studies in 143B osteosarcoma cancer cells
Download2006
Abrams, D., Huang, Y., McQuarrie, S., Roa, W., Chen, H., Löbenberg, R., Azarmi, S., Miller, G. G., Finlay, W. H.
Abstract: PURPOSE: To establish a matrix of parameters to synthesize nanoparticles of different sizes and to investigate the cellular uptake of these nanoparticles by osteosarcoma cancer cells in order to investigate their potential as therapeutic drug-delivery carriers. METHODS: Gelatin A and B...
-
Poly n-butylcyanoacrylate (PNBCA) nanocapsules as a carrier for NSAIDs: in vitro release and in vivo skin penetration
Download2003
Kubo, W., Takahashi, A., Miyazaki, S., Löbenberg, R., Bachynsky, J.
Abstract: Purpose: The aim of this work was to prepare poly n-butylcyanoacrylate (PNBCA) nanocapsules loaded with indomethacin and to evaluate the ability of this carrier system to deliver the drug systemically after its topical application. Methods: Poly n-butylcyanoacrylate (PNBCA) nanocapsules...
-
Statistical evaluation of tablet coating processes: influence of pan design and solvent type
Download2010
Araci Bou-Chacra, N., Löbenberg, R., Pereira de Melo Jr., V.
Partially and fully perforated pan coaters are among the most relevant types of equipment currently used in the process of coating tablets. The goal of this study was to assess the performance differences among these types of equipment employing a factorial design. This statistical approach...
-
2023-06-07
Noyen, Meghan, Sanghera, Ravina, Kung, Janice Y, Schindel, Theresa J
Research question: How do students entering the Doctor of Pharmacy program envision pharmacists’ roles? Dataset of participants' drawings of how they envision pharmacists' roles. Underneath their drawing, they may include a few words. 100 submissions from the Class of 2025. Method: Draw and...