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Skip to Search Results- 2Coulombe, Marilyne G.
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- 1Abdel-Monem, Hanan Ahmed Fahmy.
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- 1Abofayed, Hiatem Abdullah
- 8Primary Biliary Cholangitis
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Results for "departments_tesim:"Department of Medicine""
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A Retrospective Analysis of the Safety and Efficacy of a 6-Week Pulmonary Rehabilitation Program in Patients with Severe Pulmonary Arterial Hypertension
DownloadSpring 2014
Pulmonary Arterial Hypertension (PAH) is progressive disease characterized by reduced exercise capacity and decreased quality of life. Despite the availability of disease targeted therapies outcomes remain sub-optimal. Pulmonary Rehabilitation has proven to improve outcomes in other chronic...
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A Retrospective Study on Potential Organ Donation and Transplantation Opportunities in Alberta Emergency Rooms and Intensive Care Units
DownloadFall 2018
Background: In patients with end stage organ failure, organ transplant is often the only life saving treatment. Unfortunately, worldwide, the number of organs needed for transplant far outnumber the number of organs available. This scarcity of organs has led to interest in methods of increasing...
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A Reversible Metabolic Stress-Sensitive Regulation of Collapsin Response Mediator Protein 2A Orchestrates Cytoskeletal Remodeling and EMT, Increasing Metastatic Potential in Cancer
DownloadFall 2021
Cancer represents the second leading cause of death globally only after heart disease and is responsible for about 10 million deaths per year with a significant economic impact (WHO facts). Moreover, its prevalence is projected to increase over the following decades. Among all cancers, breast,...
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A Review of the Appropriate Usage and Efficacy of Iron Replacement Therapy in Gastroenterology Inpatients: Is Intravenous Iron Overutilized?
DownloadSpring 2023
Background: Iron deficiency anemia (IDA) is highly prevalent in patients with gastrointestinal disease. Therefore, appropriate replacement therapy is an essential component of management. Both intravenous (IV) and oral (PO) iron replacement therapies (IRT) are effective. There are concerns,...
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A Study of the Protein Phosphatase 1 (PP1) Regulatory Subunit, TIMAP, in Human Glomerular Endothelial Cells
DownloadFall 2015
TIMAP is a prenylated endothelial-predominant regulatory subunit for the serine/threonine (Ser,S/Thr,T) protein phosphatase 1 catalytic subunit (PP1c). TIMAP was first discovered in glomerular endothelial cells. It is expressed in the developing blood vessels of kidney, and its transcription in...
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Spring 2022
The endomembrane system is one of the hallmark features of all eukaryotes that distinguishes them from prokaryotes. Compared to bacteria and archaea, eukaryotic cells consist of biochemically and functionally distinct membranous compartments such as the endoplasmic reticulum, the Golgi apparatus,...
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Access to Kidney Care: Global implications for workforce capacity and use of electronic consultations to facilitate kidney care
DownloadFall 2018
Chronic kidney disease (CKD) is increasingly recognized as a global public health issue due to rising prevalence, associated adverse health outcomes and substantial economic impact. To address this problem, countries need health system strengthening, and the health workforce is considered the...
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Acute Isolated Increased Renal Venous Pressure and Kidney Functions in an Experimental Rat Model
DownloadSpring 2019
Increased renal venous pressure is a recognized risk factor for kidney dysfunction. It is not rare in clinical settings with venous congestion, such as heart failure, and is associated with worsening kidney function and increased mortality. However, the underling mechanisms are not well...