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Mapping Patient and Caregiver Involvement across the Orphan Drug Lifecycle and in Programs that Provide Access to Promising Therapies While Ensuring Prudent use of Scarce Health Care Resources
DownloadFall 2016
Patients with rare diseases face significant challenges in accessing orphan drugs in Canada because of the uncertainties that decision-makers face when deciding whether or not to provide coverage for a new drug. While all coverage decisions are made under uncertainty, this uncertainty is often...
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The Clinical Adoption of anti-CD19 CAR T-cell Therapy in Alberta: A Historical Review and Retrospective Comparative Case Study
DownloadFall 2022
This thesis details the adoption of anti-CD19 CAR T-cell therapy in Alberta from 2018-2021, during which time a commercial (tisagenlecleucel) and investigative (ACT-C01) CAR T product were implemented as standard of care and under a clinical trial, respectively. Information was gathered through...