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Deletion or substitution of conserved amino acid residues at the tip of the domain IV of Tet(O) impairs tetracycline resistanceDownload
Resistance to tetracycline (Tc), an inhibitor of protein synthesis, decreases its effectiveness for the treatment of bacterial infections. Tc resistance (TcR) can be mediated by the ribosomal protection protein, Tet(O), which was first reported in Campylobacter jejuni, a cause of bacterial...
Evaluating the Persistence of Dissolved Heteroatomic Organic Chemicals in Oil Sands Process-Affected Water by Non-Targeted AnalysisDownload
Over 1 billion m3 of wastewater in tailings ponds currently awaits remediation as a result of the extraction of bitumen – the Canadian oil sands ore. Relative to the Athabasca River and regional tributaries, oil sands process-affected water (OSPW) has increased levels of salts, metals and a...
Liposome-based therapy: An alternative approach to treat Helicobacter pylori infection in high prevalence communities such as Aklavik, NWTDownload
Helicobacter pylori infects about half of the world population causing chronic gastritis, peptic ulcer or gastric cancer. The Aboriginal people in Aklavik, NWT, Canada are concerned about gastric cancer because of the high prevalence of H. pylori infection (58%) in their community. H. pylori...