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Data-Driven Approaches to Modeling Heterogeneity and Variability Across Asymptomatic Brain and Cognitive Aging, Mild Cognitive Impairment, and Alzheimer’s disease
DownloadSpring 2024
Objective We apply data-driven approaches to identify predictors of heterogeneous trajectories across normal aging, Mild Cognitive Impairment (MCI), and Alzheimer’s disease (AD). In Study 1, we investigated predictors of left and right hippocampal (HC) volume trajectory classes. In Study 2, we...
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Everyday Physical Activity and Mobility Affect Executive Function Performance and Change in Older Adults: Evaluating Independent and Moderating Effects of Genetic Risk for Alzheimer’s Disease
DownloadFall 2015
Objective: Among older adults, everyday physical activity (EPA) and mobility (MOB) are important contributors to age-related variability and change in executive functioning (EF). However, the role of these health and lifestyle influences may be moderated by genetic factors, especially those known...