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Skip to Search Results- 58Young, T. Kue
- 14Nykiforuk, Candace I.J.
- 10Bjerregaard, Peter
- 10Chatwood, Susan
- 10Hegele, Robert A.
- 7Connelly, Philip W.
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Forecasting Pharmaceutical Prices for Economic Evaluations When There Is No Market: A Review
Download2017-07-12
Tien Dat Tran, Ilke Akpinar, Philip Jacobs
Background Economic evaluation helps policy makers and healthcare payers make decisions on drug listing, coverage, and reimbursement. When economic evaluations are conducted before a product launch, the prices of the pharmaceuticals have to be forecast. Objective The aim of this study was to...
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1999-08-04
Hegele, Robert A., Anderson, Carol, Young, T. Kue, Connelly, Philip W.
"The GNB3 825T allele encodes a product that has enhanced activation of heterotrimeric G proteins in vitro and could play a role in adipogenesis. We therefore evaluated the possibility that the GNB3 825T allele was associated with obesity in a sample of 213 healthy Canadian Inuit. We found that...
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2013-01-01
Caulfield, Timothy, Chandrasekharan, Subhashini, Joly, Yann, Cook-Deegan, Robert
There has been much investment in research on the ethical, legal and social issues (ELSI) associated with genetic and genomic research. This research should inform the development of the relevant policy. So far, much of the relevant policy - such as in the areas of patents, genetic testing and...
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2016
Young, T. Kue, Chatwood, Susan, Marchildon, Gregory, P.
"To determine if Canadians are getting value for money in providing health services to our northern residents. Secondary analyses of data from Statistics Canada, the Canadian Institute of Health Information and territorial government agencies on health status, health expenditures and health...
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How perceptions of community environment influence health behaviours: using the Analysis Grid for Environments Linked to Obesity Framework as a mechanism for exploration
Download2016-09-01
Belon, A.P., Schopflocher, D., Nykiforuk, C.I., Plotnikoff, , Nieuwendyk, L.M., Raine, K.D., Vallianatos, H., Spence, J.C.
Introduction: Overweight and obesity are influenced by a complex interplay of individual and environmental factors that affect physical activity and healthy eating. Nevertheless, little has been reported on people's perceptions of those factors. Addressing this critical gap and community partner...
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How we identify and count Aboriginal people—does it make a difference in estimating their disease burden?
Download2013
Chan,W. W., Ng, C., Young, T. K.
"Introduction: We examined the concordance between the Canadian Community Health Survey (CCHS) 'identity' and 'ancestry' questions used to estimate the size of the Aboriginal population in Canada and whether the different definitions affect the prevalence of selected chronic diseases. Methods:...
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2012
Birkholz.D., Genuis, S. J., Beesoon, S., Lobo, R.
Background. Individual members of the phthalate family of chemical compounds are components of innumerable everyday consumer products, resulting in a high exposure scenario for some individuals and population groups. Multiple epidemiological studies have demonstrated statistically significant...
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2012
Birkholz, D., Lobo, R., Beesoon, S., Genuis, S.J.
Background. Bisphenol A (BPA) is an ubiquitous chemical contaminant that has recently been associated with adverse effects on human health. There is incomplete understanding of BPA toxicokinetics, and there are no established interventions to eliminate this compound from the human body. Using 20...
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Identification of a novel lipase gene mutated in lpd mice with hypertriglyceridemia and associated with dyslipidemia in humans
Download2003-05-13
Wen, Xiao-Yan, Hegele, Robert A., Wang, Jian, Wang, Ding Yan, Cheung, Joseph, Wilson, Michael, Yahyapour, Maryam, Bai, Yahong, Zhuang, Lihua, Skaug, Jennifer, Young, T. Kue, Connelly, Philip W., Koop, Ben F., Tsui, Lap-Chee, Stewart, A. Keith
"Triglyceride (TG) metabolism is crucial for whole body and local energy homeostasis and accumulating evidence suggests an independent association between plasma TG concentration and increased atherosclerosis risk. We previously generated a mouse insertional mutation lpd (lipid defect) whose...