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Skip to Search Results- 150Chemistry, Department of
- 144Chemistry, Department of/Journal Articles (Chemistry)
- 6Chemistry, Department of/Research Data and Materials (Chemistry)
- 1Human Ecology, Department of
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- 69Klassen, John S.
- 52Kitova, Elena N.
- 17Serpe, Michael J.
- 13Macauley, Matthew S.
- 12Liu, Lan
- 10El-Hawiet, Amr
- 20Electrospray ionization mass spectrometry
- 12Affinity
- 11Complexes
- 10Carbohydrates
- 8Binding
- 8Etalons
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Impact of the nature and size of the polymeric backbone on the ability of heterobifunctional ligands to mediate Shiga toxin and serum amyloid P component ternary complex formation.
Download2011
Mulvey, G. L., Bundle, D. R., Deng, Z., Armstrong, G. D., Sadowska, J .M., Paszkiewicz, E., Griener, T., Ahmed, M., Narain, R., Kitov, P. I.
Inhibition of AB(5)-type bacterial toxins can be achieved by heterobifunctional ligands (BAITs) that mediate assembly of supramolecular complexes involving the toxin's pentameric cell membrane-binding subunit and an endogenous protein, serum amyloid P component, of the innate immune system....
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Indole-3-Acetic Acid is produced by Emiliania Huxleyi Coccolith-bearing cells and triggers a physiological response in bald cells
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Bramucci, Anna R., Labeeuw, Leen, Khey, Joleen, Case, Rebecca J., de la Mata, A. Paulina, Harynuk, James, Atwal, Harjot
Indole-3-acetic acid (IAA) is an auxin produced by terrestrial plants which influences development through a variety of cellular mechanisms, such as altering cell orientation, organ development, fertility, and cell elongation. IAA is also produced by bacterial pathogens and symbionts of plants...
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2016
Klassen, John S., Yao, Yuyu, Kitova, Elena N., Richards, Michele R.
The results of an investigation into the influence of sulfolane, a commonly used supercharging agent, on electrospray ionization mass spectrometry (ESI-MS) measurements of protein–ligand affinities are described. Binding measurements carried out on four protein–carbohydrate complexes, lysozyme...
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2016
Klassen, John S., Yao, Yuyu, Kitova, Elena N., Richards, Michele R.
The results of an investigation into the influence of sulfolane, a commonly used supercharging agent, on electrospray ionization mass spectrometry (ESI-MS) measurements of protein–ligand affinities are described. Binding measurements carried out on four protein–carbohydrate complexes, lysozyme...
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2016-06-22
Jia, Feng, Howlader, Md. Amran, Cairo, Christopher W.
Integrins are critical receptors in cell migration and adhesion. A number of mechanisms are known to regulate the function of integrins, including phosphorylation, conformational change, and cytoskeletal anchoring. We investigated whether native neuraminidase (Neu, or sialidase) enzymes which...
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Investigation of the Accelerated Thermal Aging Behavior of Polyetherimide and Lifetime Prediction at Elevated Temperature
Download2023-01-01
Cho C., Nam S.L., de la Mata P.A., Harynuk J.J., Elias A., Chung H-J, Dolez P.I.
Fire-protective clothing are manufactured using heat and flame resistant fibers that are made of high-performance polymers. These polymers exhibit a gradual reduction in their performance after long-term exposure under various aging conditions. This study investigates the thermal aging behavior...
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Light switchable optical materials from azobenzene crosslinked poly(N-isopropylacrylamide)-based microgels
Download2014
Serpe, Michael J., Zhang, Qiang M., Li, Xue, Islam, Molla R., Wei, Menglian
4,40 -Di(acrylamido)-azobenzene was used as a crosslinker in poly(Nisopropylacrylamide)-based microgels. The microgels were subsequently used to fabricate microgel-based optical materials (etalons), which exhibited optical properties that were switchable upon exposure to UV irradiation. We also...
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2015
Berg, Darren, Mugo, Samuel M., Zhang, Qiang M., Serpe, Michael J.
Lipase-modified pH-responsive poly(N-isopropylacrylamide)-based microgels were synthesized. An optical device was subsequently fabricated by sandwiching the enzyme loaded responsive microgels between two thin Au layers, and their response to triolein, a model triglyceride, was investigated. The...
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Localizing carbohydrate binding sites in proteins using hydrogen/deuterium exchange mass spectrometry
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Kitova, Elena N., Klassen, John S., Eugenio, Luiz, Li, Jun, Ng, Kenneth, Zhang, Jingjing
The application of hydrogen/deuterium exchange mass spectrometry (HDX-MS) to localize ligand binding sites in carbohydrate-binding proteins is described. Proteins from three bacterial toxins, the B subunit homopentamers of Cholera toxin and Shiga toxin type 1 and a fragment of Clostridium...
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Localizing carbohydrate binding sites in proteins using hydrogen/deuterium exchange mass spectrometry
Download2016
Klassen, John S., Kitova, Elena N., Li, Jun, Zhang, Jingjing, Ng, Kenneth, Eugenio, Luiz
The application of hydrogen/deuterium exchange mass spectrometry (HDX-MS) to localize ligand binding sites in carbohydrate-binding proteins is described. Proteins from three bacterial toxins, the B subunit homopentamers of Cholera toxin and Shiga toxin type 1 and a fragment of Clostridium...