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Fall 2023
The overarching idea of this thesis stemmed from previous work in our lab, where it was noticed that females and males exhibited different disease trajectories in a model of Multiple Sclerosis. Combined with our observation of different outcome metrics for peripheral nociception suggested that...
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Peripheral contribution to pain hypersensitivity in a T-cell mediated model of multiple sclerosis: The female perspective
DownloadSpring 2020
Multiple sclerosis (MS) is a neuroinflammatory disease characterised by immune activation, demyelination, and degeneration in the central nervous system (CNS). Chronic pain is a common symptom of MS and current treatment options for pain in MS are ineffective. Pain arises from aberrant...