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Skip to Search Results- 1 Lansing, Marihan
- 1Abu Alrub, Osama Y
- 1Ahrari, Malema
- 1Ali, Amber Z
- 1Ali, Noureen
- 1Allan, Chantal J
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Role of Glucagon-like Peptide-2 and Elemental Formula in Short Bowel Syndrome – Using Neonatal Piglets as an Animal Model
DownloadSpring 2012
Recovery from short bowel syndrome (SBS) requires intestinal adaptation, dependent on enteral nutrition (EN) and peptides, like glucagon-like peptide-2 (GLP-2). The purpose of this thesis was to investigate endogenous GLP-2 production and compare elemental versus polymeric formula in a neonatal...
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Fall 2014
Cardiac Fatty acids β-oxidation (FAO) markedly increases during maturation and become the major source of energy for the adult heart. However, excessive rates of FAO can compromise cardiac function in obesity, diabetes, and heart failure. Lysine acetylation has recently been identified as a...
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Fall 2012
Melanoma has the most rapidly rising incidence of all cancers and once metastasized it is very difficult to treat. This makes the identification of molecular pathways that are deregulated in melanoma a novel area of study. β-catenin (β-cat) is a multifunctional protein of the Wnt signaling...
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Spring 2016
Osteosarcoma (OS) is the most common primary bone malignancy with a high incidence in children and adolescents. Current treatment strategies (surgery and adjuvant chemotherapy) has improved the overall survival rate of patients with primary OS. However, the survival rate of patients with...
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Fall 2021
Each year, 10-20% of newborns (about 13-26 million babies) worldwide will need help to breathe at birth. Helping babies breathe is the cornerstone of neonatal resuscitation. Healthcare providers (HCPs) must perform many tasks quickly and correctly to help babies breathe and prevent irreversible...
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Sex-specific Changes in Neonatal Cardiac Mitochondria in Response to Perinatal Iron Deficiency
DownloadFall 2023
Introduction: Iron deficiency (ID) during gestation has been shown to alter growth and developmental trajectories, consequentially increasing the risk of long-term cardiovascular dysfunction in offspring. The heart becomes energetically dependent on mitochondria soon after birth and disturbances...
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Single Centre Experience with Hypoxic Ischemic Encephalopathy: Prognostic Factors and Development of a Prognostication Model
DownloadFall 2022
Hypoxic ischemic encephalopathy (HIE) continues to carry prognostic uncertainty despite therapeutic hypothermia (TH) becoming standard of care in high income nations. Prognostic factors have been identified with recent evidence relying on factors that are available later in a hospital admission...
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Sleep Duration and the Gut Microbiota in Infancy: an exploration of the determinants of sleep and the association between sleep and the gut microbiota at 3 months of age in a Canadian birth cohort
DownloadSpring 2019
RATIONALESleep duration is critical to growth, cognitive development, and overall health status in infancy. Strategies to ensure that national recommendations for sleep duration in infants are met require knowledge of perinatal factors that affect infant sleep. Parental socioeconomic status...
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Social Participation and its Classification for Preschool Children with Autism Spectrum Disorder
DownloadFall 2016
Background. Social participation is considered the ultimate aim of rehabilitation, particularly for preschool children with Autism Spectrum Disorder (ASD). Given the inherent social difficulties of preschool children with ASD, social participation is a relevant and meaningful construct to explore...
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Fall 2013
ATP-binding cassette transporter G1 (ABCG1) mediates sterol efflux onto lipidated lipoproteins and plays an important role in macrophage cholesterol homeostasis. In this project, we investigated how ABCG1 works as a functional transporter to mediate sterol translocation. First, we found a...