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Skip to Search Results- 2Molina-de-Orozco, Vivian Regina, 1955-
- 1Abou Marak Dit Roum, Darine
- 1Aguilar, Hector N
- 1Al-Momany, Abass M T
- 1Al-Zubaidy, Zaidoon A.
- 1Aljunaidy, Mais
- 5Calcium
- 4Calcium channels
- 4Pregnancy
- 3Aortic aneurysm
- 3Biological transport. Regulation.
- 3Blood-vessels. Dilatation.
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Fall 2016
Intravascular volume is maintained by complex interplay between organ systems with a main role for renal sodium, and water handling. The glomerulus filters a large quantity of water and salt daily with the majority of sodium, water and calcium being reabsorbed from the proximal tubule (PT). The...
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Fall 2012
The kidney anion exchanger 1 (kAE1) is crucial in the regulation of physiological pH by facilitating Cl-/HCO3- exchange. Inability to do so results in distal renal tubular acidosis (dRTA), which is more often due to mutations leading to mis-localization of kAE1, rather than complete abolishment...
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Spring 2011
The developing chick retina is an extrapituitary site of growth hormone (GH) synthesis and action. GH, GH receptor (GHR) and their mRNAs are present in the neural retina when the neural cells are undergoing proliferation and differentiation during early embryogenesis. It is thus likely that GH...
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Rho-Kinase-Mediated Diphosphorylation of Myosin Regulatory Light Chain is a Unique Biochemical Mechanism in Human Uterine Myocytes
DownloadFall 2011
Rationale: Smooth muscle (SM) contraction results from activation of the cellular contractile machinery by phosphorylation of myosin regulatory light chain (RLC) at S19 (pRLC) by RLC kinase (MLCK). Subsequent phosphorylation at T18 yields diphosphorylated-RLC (ppRLC), which has been shown to...
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Role of A Disintegrin and Metalloproteinases (ADAMs)- 15 and 17 in Cardiac Remodelling Following Pressure Overload
DownloadSpring 2024
Myocardial remodeling is a critical process in response to cardiac stress or injury, which includes changes in the cardiomyocyte size, the extracellular matrix (ECM), and cell-ECM interactions. Cardiac hypertrophy is the morphological increase in the myocardial mass by an increase in the...
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Role of Disintegrin and Metalloproteinase 17 (ADAM17) in Hypertension and Thoracic Aortic Aneurysm
DownloadFall 2018
Hypertension is a major risk factor for cardiovascular complications such as stroke, myocardial infarction, heart failure, and renal failure, and therefore is an enormous healthcare burden worldwide. The renin-angiotensin system (RAS) is an essential regulator of blood pressure homeostasis, and...
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Spring 2023
Atherosclerosis and aortic aneurysms are two major vascular diseases, and extracellular matrix (ECM) plays an important role in both as a non-cellular component of the aortic wall that also regulates vascular cell behavior and function. Atherosclerosis is a major contributor to cardiovascular...