This decommissioned ERA site remains active temporarily to support our final migration steps to https://ualberta.scholaris.ca, ERA's new home. All new collections and items, including Spring 2025 theses, are at that site. For assistance, please contact erahelp@ualberta.ca.
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Fall 2017
Metastasis is the leading cause of cancer-related deaths, yet there are no therapies that directly target this process. To identify potential therapeutic targets of metastatic dissemination, we recently completed the first whole human genome shRNA screen using a novel avian embryo intravital...
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Fall 2014
Chemoresistance is one of the major hurdles to induce a cure in patients with epithelial ovarian cancer (EOC). RUNX3, belonging to the family of RUNX transcription factors, has been shown to act in an oncogenic manner by promoting proliferation and colony formation when overexpressed, in EOC....
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The Role of the Androgen Receptor in Prostate Cancer-induced Platelet Aggregation and Invasion
DownloadFall 2019
Background: Prostate cancer (PCa) is the most common visceral malignancy and third leading cause of cancer death among men in Canada. The 2018 Canadian Cancer Society estimates suggest that 21,300 men were diagnosed and 4,100 patients died of this disease. Metastatic prostate cancer (mPCa) is...
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Spring 2020
To ensure faithful cell division, entry into mitosis must be inhibited in cells with damage or under-replicated DNA. Wee1 and Myt1 are two partially redundant kinases that inhibit mitotic entry through the phosphorylation of the Cdk1/cyclin B complex. Cdk1 is an essential mitotic kinase that...
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Time Domain Principal Component Analysis for Rapid, Real-Time 2D MRI Reconstruction from Undersampled Data
DownloadSpring 2022
Hybrid Linac-MR systems are becoming more mainstream for use in external beam radiotherapy treatments for cancer patients. The addition of an MR scanner to a linear accelerator (Linac) can allow for real-time structure tracking (such as a tumour) and on-the-fly adjustments of the radiation beam....
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Spring 2022
Ovarian cancer is the most lethal gynecological cancer, and epithelial ovarian cancer (EOC) accounts for about 90% of ovarian cancers. Despite advancements in medical technology, the overall survival rate of EOC has improved only slightly, with a 5-year survival rate of less than 50%. One cause...
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Fall 2016
Breast cancer (BrCa) is the most common cancer and the leading cause of cancer-related deaths in women worldwide. Current therapies for BrCa are insufficient to cure metastatic disease and are often associated with debilitating side effects that severely deteriorate the quality of patients’...