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Skip to Search Results- 1Adam, Ibrahim S. Y.
- 1Airo, Adriana M
- 1Arendt, Christopher William.
- 1Awadh, Abdullah
- 1Azaizeh, Bara'ah
- 1Bacik, John-Paul
- 8Evans, David (Medical Microbiology and Immunology)
- 6Foley, Edan (Medical Microbiology and Immunology)
- 5Barry, Michele (Medical Microbiology and Immunology)
- 5Ingham, Robert (Medical Microbiology and Immunology)
- 5Ostergaard, Hanne (Medical Microbiology and Immunology)
- 4Baldwin, Troy (Medical Microbiology and Immunology)
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Biochemical Characterization and Inhibition of Influenza B Virus RNA-Dependent RNA Polymerase
DownloadSpring 2021
The influenza virus can cause severe respiratory illness in humans and animals. There are four types of influenza viruses (A, B, C, and D); however, only type A and B cause severe diseases in humans. Influenza virus belongs to the family Orthomyxoviridae, which includes segmented negative-sense...
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Biochemical Studies on the Mechanism of Action of Remdesivir and Other Nucleotide Analog Polymerase Inhibitors during the COVID-19 Pandemic
DownloadFall 2024
Several disease-causing RNA virus families, capable of infecting humans, remain a significant global health threat due to the lack of effective medical countermeasures. This was perhaps best exemplified early in the COVID-19 pandemic when spread of severe acute respiratory syndrome coronavirus 2...
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Spring 2014
The fine balance struck between life and death is key for the health of all multicellular organisms and therefore the pathways that govern life and death decisions are evolutionarily highly conserved. For example, the human TNF and the Drosophila IMD pathways coordinate signaling elements such...
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Fall 2021
Viral infection accounts for significant morbidity, mortality, and economic loss worldwide. At no time in modern history has this been more apparent than it is now given the current global pandemic. This problem is compounded by the emergence of viral strains resistant to currently available...
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Fall 2013
Vibrio cholerae is the Gram-negative bacterium responsible for the diarrheal disease cholera. In addition to the well-characterized virulence factors – cholera toxin and the toxin co-regulated pilus – used by this organism to cause watery diarrhea, V. cholerae uses the type VI secretion system...
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Characterization of Binding of LILRA3 and LILRB2 to the Myelin-Associated Inhibitors and Major Histocompatibility Class I Molecules
DownloadFall 2018
The leukocyte immunoglobulin-like receptor family (LILR) is composed of inhibitory and activating receptors that are widely expressed on immune cells and interact with classical and non-classical MHC-I. Recently, several ligands have been identified for the LILRs including the three...