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- 24Chemistry
- 23Organic compounds. Synthesis.
- 22Metabolomics
- 21Capillary electrophoresis.
- 21Catalysis
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Fall 2016
This work covers the general scope of stimuli-responsive polymers, with the special focus on the thermoresponsive poly (N-isopropylacrylamide) (pNIPAm)-based hydrogels and particles (microgels) and their composites, humidity responsive polyelectrolyte-based bilayer devices, and their applications...
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Fall 2020
Pereira Carvalho, Wildemar Stefanio
We have witnessed significant progress in the past few decades in the development of stimuli-responsive polymer-based smart materials. A great deal of work has been dedicated to the development of sensors and biosensors that are portable, inexpensive and easy-to-use to be used in resource limited...
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Stimuli-Responsive Polymer-Based Devices for Surface Plasmon Resonance Spectrometer Sensing
DownloadSpring 2018
Surface plasmon resonance (SPR) has emerged as a powerful tool in sensing and biosensing for decades due to its label free and real-time data collection characteristics. In the first part of this thesis, a custom-built high performance SPR spectrometer with broad range of scanning angle, high...
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Stimuli-Responsive Polymer-Based Materials and Devices for Controlled and Triggered Release of Small Molecules
DownloadSpring 2020
This thesis covers the general scope of stimuli-responsive polymers and the concept of controlled drug delivery, with special focus on controlled/triggered release applications of temperature-responsive poly (N-isopropylacrylamide) (pNIPAm)-based hydrogels, microgels, their assemblies, and...
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Structural and Inhibitory Studies of LL-Diaminopimelate Aminotransferase and Investigation of Methods for Small Peptide Crystallization
DownloadFall 2012
The pyridoxal-5'-phosphate (PLP)-dependent enzyme LL-diaminopimelate aminotransferase (LL-DAP-AT) catalyzes a key step in the biosynthesis of L-lysine in plants and Chlamydia. In this thesis, studies of mechanistic and inhibitory aspects of LL-DAP-AT are described. Two LL-DAP-ATs from...
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Spring 2016
The lipopeptides, tridecaptin A1, tridecaptin B1 and cerexin A1 were isolated from Paenibacillus terrae NRRL B-30644, Paenibacillus polymyxa NRRL B-30507 and Bacillus mycoides ATCC 21929, respectively. A combination of chemical synthesis, peptide derivatization, high performance liquid...
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Fall 2014
Paenibacillus polymyxa NRRL B-30509, Paenibacillus terrae NRRL B-30644 and P. polymyxa NRRL B-30507 were found to produce several bacteriocins and non-ribosomal peptides. All three strains produce tridecaptins, non-ribosomal lipopeptides antimicrobially active against food pathogen Campylobacter...