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Skip to Search Results- 2Chun, Justin
- 1Aktary, Zackie M
- 1Anderson, Andrea Marie
- 1Anderson-Baron, Matthew N
- 1Armstrong, Heather K
- 1Baier, Alicia
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Fall 2017
The nucleus is a hallmark of eukaryotic cells. It segregates the genetic material from the cytoplasm. The nucleus is encapsulated by the nuclear envelope which is perforated with nuclear pore complexes (NPCs), macromolecular structures formed by proteins termed nucleoporins (Nups). NPCs and...
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Fall 2009
Oxidative protein folding within the ER depends on the enzymatic action of numerous chaperones and oxidoreductases. In addition, this process requires the influx of metabolites and energy, including FAD (flavin adenine dinucleotide) and molecular oxygen. Secretory proteins and proteins destined...
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Spring 2013
The mitochondria associated membranes (MAMs) of the endoplasmic reticulum (ER) are the points of contact between the ER, which is the organelle responsible for lipid and secreted protein synthesis and calcium storage, and the mitochondria, which are organelles responsible for cellular energy...
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Spring 2019
Organelles serve to compartmentalize biochemical functions within the eukaryotic cell. However, to collectively maintain cellular homeostasis, organelles must communicate in some way in order to coordinate these functions. Two such organelles,the peroxisome and the lipid droplet, are both...
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Fall 2011
Myristoylation involves the addition of a 14-carbon fatty acid to the N-terminal glycine of proteins by N-myristoyltransferase. Myristoylation promotes protein-membrane and protein-protein interactions that are crucial for the function of myristoylated proteins. Myristoylation occurs...
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Spring 2013
Prions are infectious proteins. In their prion conformation, they catalyze the transformation of non-prion isomers into prions. Another characteristic common to currently identified prions is that they form amyloid aggregates. They occur in several mammals and multiple species of yeast, acting in...
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Fall 2013
Ortiz Sandoval, Carolina Guadalupe
The ER mitochondria-associated membrane (MAM) is a hub for many calcium-mediated processes required for cell survival, including apoptosis, autophagy, and ATP production. In this thesis, we identified and characterized the interaction between MAM-enriched Rab32 and its effector Drp1, a master...