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Skip to Search Results- 2Sapkota, Shraddha
- 1Aglah, Conrad
- 1Ahmetovic, Alisa
- 1Alles, Sascha R
- 1Alpaugh, Melanie J
- 1Alston, Lauren L
- 13Spinal cord injury
- 7Rats. Nervous system.
- 7Stroke
- 6Human locomotion.
- 6Microglia
- 6Spinal cord. Wounds and injuries. Animal models.
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Fall 2017
Prion disease, or transmissible spongiform encephalopathy (TSE), is a type of neurodegenerative disease for which there is no treatment and which is invariably fatal. Prion diseases are distinct in the field of biology and medicine, not only because they can be sporadic, infectious, or inherited,...
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Changes in collateral blood flow and neuroprotective efficacy of transient aortic occlusion during acute ischemic stroke
DownloadSpring 2014
Ischemic stroke is the rapid loss of brain function due to occlusion of a cerebral blood vessel. It is a major cause of death and disability in the world; however, the approved thrombolytic treatments are ineffective in many patients and there is a need for better therapies for treating brain...
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Characterisation of the sleep-related slow oscillation in the neocortical - entorhinal - hippocampal bidirectional circuit
DownloadFall 2009
Our ability to recall information and events is astounding and dependent on the medial temporal lobe (MTL) memory system. The synaptic interconnections between the neocortex (nCTX), entorhinal cortex (EC), and hippocampus (HPC) are the anatomical basis of this memory system. The...
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Spring 2017
Characterization of Spinal Cord Microglia. Previous studies suggest that the functional response properties of activated brain microglia varied according to the brain region they were derived from, suggesting that these activation profiles are a function of their local environment. CNS microglia...
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Characterizing the mode of action of super long-acting beta2-adrenergic receptor agonists: A more effective therapeutic for Parkinson's disease.
DownloadFall 2016
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by a loss of dopaminergic neurons in the Substantia nigra (SN) resulting in hypokinetic motor movements. The long-acting beta2-adrenergic receptor (β2-AR) agonist salmeterol has been shown to be neuroprotective in animal...
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Spring 2013
Alzheimer’s disease (AD) is a complex neurodegenerative disorder believed to be triggered by the accumulation of β-amyloid (Aβ)-related peptides derived from the proteolytic processing of amyloid precursor protein (APP). Research over the last two decades has shown that alterations in the levels...
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Fall 2013
Background: Ischemic stroke is associated with cognitive impairment, but the acute cognitive sequelae of transient ischemic attack (TIA) and minor stroke is unknown. We hypothesized that transient cognitive impairment can be predicted by diffusion-weighted imaging (DWI) lesion volume. Methods:...
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Connectivity and Regional Distribution of Constituent Cells of the Mammalian Locomotor Central Pattern Generator
DownloadFall 2016
The mammalian spinal cord contains a network of neurons capable of generating the rhythm and coordinating the complex motor pattern which underlies overground locomotion. This network, called the locomotor central pattern generator (CPG), can operate in isolation from afferent input and...