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Characterizing Cerebral Degeneration in Amyotrophic Lateral Sclerosis with Texture Analysis
DownloadFall 2020
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is hallmarked by unrelenting and progressive wasting and paralysis of voluntary muscles. The classic pathology in ALS features neuronal loss, gliosis, and abnormal protein deposition in the upper and lower motor neurons (UMN...
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DETECTING CEREBRAL DEGENERATION IN ALS USING A MULTICENTRE APPLICATION OF 3D TEXTURE ANALYSIS
DownloadFall 2018
Amyotrophic lateral sclerosis (ALS) is a highly heterogeneous disease in terms of its clinical presentation, progression, and detected pathology in the body. It is a multi-system degenerative disorder, though a diagnosis is made based on the presence of both upper motor neuron (UMN) and lower...
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Regularized Tensor Quantile Regression for Functional Data Analysis with Applications to Neuroimaging
DownloadFall 2019
With accelerating technological advancements, functional data analysis is of ever-growing importance in statistics, engineering, and medicine as the collection, storage, and analysis of data becomes ingrained in every aspect of modern life beyond any one field of study. From continuous biometric...