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Arsenic Cellular Handling by Human Multidrug Resistance Protein 1 (MRP1/ABCC1) and MRP4 (ABCC4)
DownloadFall 2021
Arsenic is a proven human carcinogen to which hundreds of millions of people are chronically exposed at unsafe levels, primarily through contaminated drinking water. An environmentally ubiquitous metalloid, arsenic in different forms is currently being used therapeutically as an anti-cancer...
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Fall 2018
Chronic exposure to arsenic from groundwater is one of the greatest public health concerns in the world, putting over 170 million people at risk of arsenic-related diseases, including cancer, diabetes, and cardiovascular disease. Although our understanding of the mechanisms by which arsenic...
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Fall 2020
Over 200 million people worldwide are exposed to the proven human carcinogen arsenic, due to contaminated drinking water. Animal studies have shown that arsenic and the essential trace element selenium can undergo mutual detoxification through the formation of the seleno-bis(S-glutathionyl)...