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- 3Victoria Longitudinal Study
- 1APOE genetic risk
- 1Alzheimer's genetic risk
- 1Apolipoprotein E
Subjective memory decline and associations with non-demented memory aging: The moderating role of genetic risk, vascular dysfunction and sexDownload
INTRODUCTION: Subjective memory decline (SMD), defined as a self-perceived change in memory function without objective impairment, has been identified as a potential early marker of cognitive decline and other Alzheimer’s disease (AD) related outcomes. A standard approach to SMD assessment...
Everyday Physical Activity and Mobility Affect Executive Function Performance and Change in Older Adults: Evaluating Independent and Moderating Effects of Genetic Risk for Alzheimer’s DiseaseDownload
Objective: Among older adults, everyday physical activity (EPA) and mobility (MOB) are important contributors to age-related variability and change in executive functioning (EF). However, the role of these health and lifestyle influences may be moderated by genetic factors, especially those known...
Apolipoprotein E (APOE) ɛ4 and Clusterin (CLU) C alleles are risk factors for Alzheimer’s disease (AD) and preclinical cognitive and memory decline in older adults. We investigated whether memory resilience to genetic risk (i.e., Apolipoprotein E [APOE] ɛ4, Clusterin [CLU] CC, and a high additive...