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Skip to Search Results- 2DNA damage
- 2Ultraviolet light
- 12-aminopurine
- 1Capillary electrophoresis
- 1Chimeric RNA DNA probe
- 1Cyclobutane pyrimidine dimer
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Development and application of a capillary electrophoresis immunoassay for DNA lesions induced by ultraviolet light
DownloadSpring 2011
Ultraviolet (UV) light is one of the most abundant DNA damaging agents. The major DNA lesions, such as cyclobutane pyrimidine dimers (CPDs) and (6-4) pyrimidine pyrimidone (64PPs) photoproducts, are carcinogenic and mutagenic. Studies of the formation, repair and mutagenicity of these DNA lesions...
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Spring 2013
Absorption of UV light by nucleic acids can result in the formation of molecular lesions leading to mutagenesis, carcinogenesis, and cell death. Thus, understanding DNA damage is important for elucidating the molecular mechanisms of disease. Much effort has been focused on developing methods for...