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Skip to Search Results- 1Caballero, Hebert S
- 1Duvall, Michael
- 1Elezzabi, Muhammad A.
- 1Fuite, Jim
- 1Funamoto, Allyson
- 1Julien, Olivier
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Fall 2010
Previous studies of the grey wolf (Canis lupus) using microsatellites have showed strong population structure despite the high mobility of individuals. I re-assessed the structure of North American grey wolves by genotyping 132 wolves at a genome-wide set of >26 000 single nucleotide...
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Spring 2010
More than 90% of human genes undergo a processing step called splicing, whereby non-coding introns are removed from initial transcripts and coding exons are ligated together to yield mature messenger RNA. Roughly 50% of human genetic diseases correspond to aberrant splicing. Splicing is...
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Fall 2012
Thuricin CD, a two-component bacteriocin produced by Bacillus thuringiensis DPC 6431, exhibits potent activity against the hospital superbug Clostridium difficile ribotype O27. The two peptides (Trn-α and Trn-β) that constitute thuricin CD operate synergistically to kill sensitive bacteria at...
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Structure and dynamics of biomolecules: probing muscle regulation, prion protein unfolding, and drug insertion into DNA by nuclear magnetic resonance spectroscopy
DownloadSpring 2011
Nuclear magnetic resonance (NMR) spectroscopy is a powerful approach to study the structure and dynamics of macromolecules in a close-to-native solution environment. In the present thesis I present my investigation of protein and nucleic acid structure and dynamics in a wide variety of biological...
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Fall 2019
The Himalayan orogen is segmented along its strike at the scale of hundreds of kilometres. This segmentation is apparent from along-strike changes in earthquake rupture patterns, thickness changes, deformation styles, topographic gradients, thermal evolution, and faults at oblique angles to the...
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Fall 2011
Recent shifts towards spatial issues within education are examined, and mapping is identified as particularly important. The multidisciplinary trend of complexity science is surveyed, in turn, through the lens of physics and education research. The provincial education system of Alberta is...
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Fall 2013
Sodium proton exchangers (NHEs) are polytopic membrane proteins that, in archaea, bacteria, yeast and plants, provide increased salt tolerance by removing excess toxic sodium, and in mammals regulate cell volume, growth, differentiation, proliferation, migration and apoptosis in relation to...