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Skip to Search Results- 7Placenta
- 3Animal Model
- 3Intrauterine growth restriction
- 2Pregnancy
- 1Aerobic exercise training
- 1Angiogenesis
- 1Abdalvand, Ali
- 1Athanassakis-Vassiliadis, Irene
- 1Corrigan, Jennifer
- 1Davey, Ashley
- 1Hong, Mandy
- 1Hunziker, Rosemarie D.
- 2Department of Agricultural, Food, and Nutritional Science
- 2Department of Medical Sciences
- 2Department of Physiology
- 2Medical Sciences- Obstetrics and Gynecology
- 1Centre for Neuroscience
- 1Department of Immunology
- 1Ambrose, Divakar (Department of Agricultural, Food and Nutritional Science)
- 1Bell, Rhonda (Department of Agricultural, Food, and Nutritional Science)
- 1Davidge, Sandra (Obstetrics and Gynecology / Physiology)
- 1Davidge, Sandra T (Department of Physiology, Department of Obstetrics and Gynaecology)
- 1Davidge, Sandra T (Obstetrics and Gynecology/ Physiology)
- 1Guilbert, Larry J (Medical Microbiology and Immunology
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Bilateral Uterine Artery Ligation in Rats cultivates Long Term Neurological Deficits reminiscent of Human Cerebral Palsy: A model for Therapeutic Intervention.
DownloadFall 2015
Introduction Cerebral Palsy (CP) is a ubiquitous term used to describe a group of permanent, non-progressive disorders of movement, posture, and behaviour. Despite countless advances in neonatal medicine, the incidence of CP has remained constant in term infants over the last three decades. More...
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Cardiovascular Effects of Aerobic Exercise Training in Hypoxic-induced Intrauterine Growth Restriction
DownloadFall 2017
Fetal hypoxia is one of the most common consequences of complicated pregnancies worldwide. It has been demonstrated that prenatal hypoxia leads to intrauterine growth restriction (IUGR). Being born growth restricted is associated with a decrease in cardiomyocyte proliferation, an increased...
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High fructose intake during pregnancy adversely affects insulin resistance, lipid profiles, and affects placental gene expression of nutrient transporters and angiogenesis in rat dams and their pregnant offspring
DownloadSpring 2017
Fructose intake has increased over the past several decades due to high consumption of sugary foods and drinks. In non-pregnant humans and animals, high fructose intake results in hyperlipidemia, insulin resistance and weight gain, although its effects on metabolic adaptations to pregnancy and on...
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Fall 2013
The placenta is an essential transitory fetal organ responsible for the key processes of nutrient, oxygen, and waste transfer between the mother and the fetus throughout gestation. Placental size is, importantly, known to correlate to fetal weight, and the malfunction and malformation of the...
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The Effects of Docosahexaenoic Acid (DHA) Dietary Supplementation in a Mouse Model of Stargardt-like Macular Dystrophy (STGD3)
DownloadFall 2013
Underlying mechanisms of how docosahexaenoic acid (DHA) might impact the progression of macular degeneration are unknown. We relied on the ELOVL4 mouse model of juvenile macular degeneration, STGD3, to test the hypothesis that antenatal DHA dietary supplementation (2% w/w of total fatty acid)...
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The Role of Matrix Metalloproteinase-2 in the Pathophysiology of a Reduced Utero-Placental Perfusion Pressure Model of Preeclampsia
DownloadFall 2012
Preeclampsia is a leading cause of maternal and fetal morbidity/mortality and induced preterm birth. Endothelin-1 (ET-1) is a potent vasoactive agent, shown to be involved in the vascular endothelial dysfunction of preeclampsia. Big endothelin (bigET) is cleaved to ET-1 by several enzymes...
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Spring 2011
Human Cytomegalovirus (HCMV) is the most common cause of congenital infection in newborns. One mechanism for this virus to reach the fetus is to cross the placenta through the syncytiotrophoblast layer. Accumulation and protection of pathogens in the syncytiotrophoblast could affect the systemic...