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Fall 2024
The COVID-19 pandemic accelerated the development of mRNA vaccines, yet iden- tifying the optimal mRNA sequence for human use, particularly for the SARS-CoV- 2 spike protein, remains challenging. This thesis focuses on optimizing the open reading frame (ORF), a crucial mRNA component composed of...
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Fall 2021
The ongoing COVID-19 pandemic is impacting the lives of billions of people worldwide as well as the medical and socioeconomic systems. The genomic variability of this virus makes it capable of being prevalent in humans around the world for a long time and migrating from one place to another. It...