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Subcellular Investigation of Poxvirus Coinfections and the Impact on the Evolution of Cidofovir Resistance
DownloadFall 2024
The Orthopoxviruses remain important re-emerging pathogens, yet there are only two monotherapy antiviral drugs for treating infections. One of the two approved drugs is brincidofovir, which is a prodrug of the acyclic nucleoside phosphonate cidofovir (CDV). CDV inhibits the vaccinia virus DNA...
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Synthesis, characterization, and antibacterial properties of a hydroxyapatite adhesive block copolymer
Download2014-01-01
Zhang, Qiang, Serpe, Michael J.
A novel diblock copolymer composed of bisphosphonate and pyridine oligomers has been prepared by reversible addition–fragmentation transfer (RAFT) polymerization. Ag ion was introduced into the polymer via its coordination with the pyridine groups, followed by a reduction process to obtain Ag...