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Fall 2012
Chromatin structure is important aspect of transcriptional regulation. Replication-coupled (RC) nucleosome assembly is the process of depositing newly synthesized H3-H4 onto nascent DNA behind the replication fork, mediated by the histone chaperones Asf1, CAF-1, and Rtt106. The experiments...
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Fall 2017
Herein, a new methodology is developed to replicate functions, measures and stochastic processes onto a compact metric space. Each replica object is a weak or strong modification of the original object, so many results are easily established for the replica objects and then transferred back to...
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Fall 2011
RNA polymerase III (RNAPIII) pre-initiation complexes at tRNA genes naturally cause replication fork pausing in the yeast Saccharomyces cerevisiae, and interference with replication is known to have deleterious effects on genome stability. It follows that repression of tRNA gene transcription...