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- 17Randomized controlled trials
- 5Systematic reviews
- 1Acute myocardial infarction
- 5Nursing, Faculty of
- 5Graduate Studies and Research, Faculty of
- 5Graduate Studies and Research, Faculty of/Theses and Dissertations
- 5Medicine and Dentistry, Faculty of
- 5Medicine and Dentistry, Faculty of/Alberta Research Centre for Health Evidence (ARCHE)
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A randomized, controlled trial of ginseng consumption on the immune response to a moderate exercise stress protocol in non-athletic womenDownload
Background: Ginseng is a popular herbal remedy that has been proposed to increase resistance to stress and enhance immune function. Regular moderate exercise results in an acute physiological stress that affects immune function. Objective: This study was conducted to investigate the effects of...
Applying the risk of bias tool in a systematic review of combination long-acting beta-agonists and inhaled corticosteroids for persistent asthma.Download
Background The Risk of Bias (RoB) tool is used to assess internal validity of randomized controlled trials (RCTs). Our objectives were to: 1) evaluate inter-rater agreement of the RoB tool; 2) determine the time to access supplemental study information; 3) compare the RoB tool with the Jadad...
Behavioural and developmental interventions for autism spectrum disorder: a clinical systematic review.Download
BACKGROUND: Much controversy exists regarding the clinical efficacy of behavioural and developmental interventions for improving the core symptoms of autism spectrum disorders (ASD). We conducted a systematic review to summarize the evidence on the effectiveness of behavioural and developmental...
Comparing the feasibility, acceptability, clinical-, and cost-effectiveness of mental health e-screening to paper-based screening on the detection of depression, anxiety, and psychosocial risk in pregnant women: A study protocol of a randomized, parallel-group, superiority trial.Download
Background Stress, depression, and anxiety affect 15% to 25% of pregnant women. However, substantial barriers to psychosocial assessment exist, resulting in less than 20% of prenatal care providers assessing and treating mental health problems. Moreover, pregnant women are often reluctant to...
Background Urinary incontinence is common after both radical prostatectomy and transurethral resection. Conservative management includes pelvic floor muscle training, biofeedback, electrical stimulation, compression devices (penile clamps), lifestyle changes, extra-corporeal magnetic innervation...
Introduction A research-practice gap exists between what is known about conducting methodologically rigorous randomized controlled trials (RCTs) and what is done. Evidence consistently shows that pediatric RCTs are susceptible to high risk of bias; therefore novel methods of influencing the...
Abstract: Objective To synthesise the literature on the effects of fish oil - docosahexaenoic acid ( DHA) and eicosapentaenoic acid ( EPA) - on mortality and arrhythmias and to explore dose response and formulation effects. Design Systematic review and meta- analysis. Data sources Medline,...
This is the protocol for a review and there is no abstract. The objectives are as follows: The objective of this review is to determine the effectiveness of interventions targeting behaviour and facilitating uptake of new knowledge by healthcare practitioners, patients and their family caregivers...
Background: Bias is a significant concern in pediatric randomized controlled trials (RCTs), but while there have been numerous calls for improvement in trial conduct, traditional means of education and dissemination of methodological principles have not had a substantial effect on the quality of...
Primary Outcomes Reporting in Trials (PORTal): a systematic review of inadequate reporting in pediatric randomized controlled trialsDownload
Objective: Conduct a systematic review of pediatric randomized controlled trials published in high impact journals to assess the reporting of primary outcomes and the psychometric properties of their measures. Study Design and Setting: Systematic review with screening and simultaneous data...