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- 2Genetics
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- 1Antisense
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- 1Baedke, Jessica
- 1Ferraz Albani, Luis A
- 1Ferreira Marques, Elisa
- 1Fung, Rachel D
- 1Koslowsky, Ingrid L
- 1Miles, David M
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Application of genomics-based tools leading to the identification of markers on bovine chromosome 14 influencing milk production and carcass quality traits
DownloadFall 2009
Genetic improvements in beef and dairy cattle can bring significant advances in satisfying the global food demand, which is expected to double by 2050. Several DNA markers have been identified on bovine chromosome 14 (BTA14), but low mapping resolution prevents their refinement for identification...
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Characteristics of Patients Reviewed by a Nurse Practitioner within an Outpatient Palliative Radiation Oncology Clinic
DownloadFall 2017
Cancer is a highly prevalent illness in Canada, with half of Canadians developing cancer and one quarter dying of the disease. In spite of significant advancements in cancer diagnosis and treatments, many cancers still have a poor prognosis. Palliative radiotherapy (PRT) is a common and effective...
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Combination Radiation Therapy and Oncolytic Vaccinia Virus Therapy in Preclinical Models of Glioma
DownloadSpring 2017
Gliomas are the most common primary malignant brain tumour in adults, with glioblastoma multiforme (GBM), the most common and most deadly form of glioma, making up over half of all diagnosed cancers in the brain/central nervous system. The standard of care for gliomas has remained unchanged for...
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Fall 2012
To understand the water cycle on Mars, details of mass and energy transfer between the surface and the atmosphere are of importance. A complete model, involving transient variations of the water in gaseous and solid phases in the atmosphere and the regolith, is developed and solved numerically...
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Estimation of the Evaporation Rate of an Isolated Water Microdroplet Subjected to Infrared Radiative Heating
DownloadFall 2014
A combined numerical-experimental investigation was performed to study the influence of infrared radiation on the evaporation of a single-component droplet in the range between 10 and 50 micrometers, under different environmental conditions of relative humidity and temperature of air. A numerical...
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Fall 2019
The development of efficacious anticancer therapies has significantly improved the prognosis of childhood cancer patients at the price of predisposing survivors to extensive chronic health problems. Although not fatal, reducing treatment-related hearing loss (ototoxicity) among childhood cancer...
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Spring 2017
One of the methods of study of black holes in astrophysics is based on broaden- ing of the spectrum of radiation of ionized iron atoms. The line Kα associated with iron emission at 6.4 keV is very narrow. If such an ion is revolving around a black hole, this line is effectively broadened as a...
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Regulation of collagen type I production by ionizing radiation and transforming growth factor-β1 in primary human skin fibroblasts derived from early stage breast cancer patients in relation to acute radiation-induced toxicity
DownloadFall 2011
Regulation of collagen type I (CI) in fibroblasts is critical for the onset and development of skin toxicities induced by radiation therapy (RT). Transforming growth factor beta-1 (TGF-β1) and vascular endothelial growth factor (VEGF) promote CI synthesis, while its degradation is modulated by...
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Synthesis and evaluation of an [18F]-labelled antisense oligonucleotide as an imaging probe to measure cellular response to radiation therapy
DownloadFall 2010
Antisense oligodeoxynucleotides (asODNs) show strong binding and high selectivity and can be constructed to recognize specific cellular targets such as gene regulated mRNA. Radiolabelled asODNs have the potential to image gene expression through mRNA targeting and could be a valuable tool in the...
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Spring 2013
Space-based measurements of the Earth's magnetic field are required to understand the plasma processes of the solar-terrestrial connection which energize the Van Allen radiation belts and cause space weather. This thesis describes a fluxgate magnetometer payload developed for the proposed...