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Differences in Whole Blood Gene ExpressionAssociated with Infection Time-Course andExtent of Fetal Mortality in a ReproductiveModel of Type 2 Porcine Reproductive andRespiratory Syndrome Virus (PRRSV)Infection
Download2016-04-19
Wilkinson, Jamie M., Ladinig, Andrea, Bao, Hua, Kommadath, Arun, Stothard, Paul, Lunney, Joan K., Harding, John C. S., Plastow, Graham S.
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection of pregnantfemales causes fetal death and increased piglet mortality, but there is substantial variationin the extent of reproductive pathology between individual dams. This study used RNA-sequencing to characterize the whole...
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Molecular and Machine Learning Based Characterization of Human Skeletal Muscle to Decipher Complex Biological Processes Governing Muscle Wasting in Surgical Patients with Cancer
DownloadSpring 2023
Cancer cachexia is a multifactorial syndrome characterized by progressive loss of weight (WL), muscle, and fat tissues. Skeletal muscle wasting, in particular, is strongly associated with morbidity and mortality. Understanding the pathophysiological mechanisms underlying muscle wasting in humans...