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- 3Fliegel, Larry
- 2Li, Xiuju J.
- 1Galhenage, Abeynayake T R
- 1Kemp, Grant
- 1Loppnow, Glen R.
- 1Lowen, Anice
- 3Biochemistry, Department of
- 3Biochemistry, Department of/Journal Articles (Biochemistry)
- 1Chemistry, Department of
- 1Chemistry, Department of/Journal Articles (Chemistry)
- 1Graduate Studies and Research, Faculty of
- 1Graduate Studies and Research, Faculty of/Theses and Dissertations
A novel four nuclear magnetic resonance (NMR)-tube holder is described for quantitative Raman and resonance Raman spectroscopy. This cell has advantages over other divided cell designs in producing high precision quantitation and eliminating off-axis errors. Raman spectra were obtained for both...
Brewers’ spent grain (BSG), the most abundant brewing by-product contains up to 24% (w/w) of protein on dry basis. Despite of a rich protein source, it is still mainly used as low value animal feed. This study was conducted to develop hydrolysates with antioxidant effects from BSG proteins by...
The Na+/H+ exchanger isoform 1 (NHE1) is an integral membrane protein that regulates intracellular pH by extruding an intracellular H+ in exchange for one extracellular Na+. The human NHE1 isoform is involved in heart disease and cell growth and proliferation. Although details of NHE1 regulation...
Regulation of Na+/H+ Exchanger Gene Expression: Role of a poly T rich region in regulation of expression of the NHE1 promoterDownload
In this study we examine regulation of expression of the Na+/H+ exchanger promoter in L6 and NIH 3T3 cells. We have identified a highly conserved poly(dA·dT)-rich region that appears to be important in regulation of expression of the NHE1 gene. Deletion or mutation of this region results in...
In this paper we examine the role of thyroid hormone in regulating expression of the Na+/H+ exchanger. Thyroid hormone has been reported to regulate the activity of the Na+/H+ exchanger messenger RNA in some cell types. Treatment of cardiac myocytes with 3,5′,3′-triiodothyronine results in an...