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Skip to Search Results- 7Phosphatidylcholine
- 1Acyl editing
- 1Apoptosis
- 1Arabidopsis-thaliana
- 1CTP:phosphocholine cytidylyltransferase
- 1Cardiac Dysfunction
- 1Carlin, Stephanie D
- 1Cole, Laura Kathleen
- 1Lewis, Erin D
- 1Lin, Yingyu
- 1Ling, Ji
- 1Navidghasemizad, Sahar
- 2Jacobs, Rene (Agricultural, Food and Nutritional Science)
- 2Vance, Dennis E. (Biochemistry)
- 1Field, Catherine (Agricultural, Food and Nutritional Science)
- 1Temelli, Feral (Agricultural, Food and Nutritional Science)
- 1Vance, Dennis (Biochemistry)
- 1Weselake, Randall, J (Department of Agricultural, Food, and Nutritional Science)
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Characterization of Phosphatidylcholine Metabolism in Mouse Hepatocytes after Hepatectomy and in Primary Human Hepatocytes
DownloadSpring 2012
Phosphatidylcholine (PC) is the major component of mammalian membranes and the induction of PC biosynthesis has been shown to be an essential step in cell proliferation in various cell lines. In the liver, PC biosynthesis is regulated by two pathways: the CDP-choline and the...
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Fall 2016
Choline is an essential micronutrient with increased requirements during pregnancy and lactation due to a high demand by the developing fetus and infant. Animal studies have demonstrated that choline is essential for brain development, and as a component of all cell membranes it is hypothesized...
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Functional Characterization of Plant Patatin-like Phospholipase A III in Transgenic Arabidopsis thaliana Producing 18 Carbon Hydroxy Fatty Acids
DownloadFall 2016
Hydroxy fatty acid (HFA)-enriched oils are valuable in many oleo-chemical industries. The major natural source of HFA, however, is castor (Ricinus communis) seed, which is poisonous to human beings and animals. Although over-expressing a castor OLEATE 12-HYDROXYLASE (RcFAH12) in Arabiodpsis...
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Spring 2013
Egg yolk contains approximately 10% (w/w) phospholipids (PL), of which about 70% is phosphatidylcholine (PC). Conventional methods of PL extraction from egg yolk involve using hazardous organic solvents. Supercritical carbon dioxide (SC-CO2), as a "green" solvent, had been applied for the...
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Insights into the role of CTP:phosphocholine cytidylyltransferase-alpha in hepatic lipid metabolism and cellular integrity
DownloadFall 2011
Lower levels of hepatic phosphatidylcholine (PC) are suggested to play a role in the pathogenesis of non-alcoholic steatohepatitis (NASH). Mice lacking hepatic CTP:phosphocholine cytidylyltransferase-α (LCTα-/-), the regulatory enzyme in the CDP-choline pathway for PC biosynthesis, were fed a...
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Insights into the Transcriptional Regulation and Physiological Importance of Phosphatidylethanolamine N-Methyltransferase
DownloadSpring 2010
Phosphatidylcholine (PC) is made in all nucleated mammalian cells via the CDP-choline pathway. Another major pathway for PC biosynthesis in liver is catalyzed by phosphatidylethanolamine N-methyltransferase (PEMT). We have identified 3T3-L1 adipocytes as a cell culture model that expresses PEMT...
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The role of de novo phosphatidylcholine synthesis in the gut-liver axis and intestinal homeostasis
DownloadSpring 2023
The intestine and liver are in constant communication to maintain lipid processes and to prevent disease states such as non-alcoholic fatty liver disease (NAFLD) and colitis. Phosphatidylcholine (PC) can be synthesized in the liver by the CDP-choline pathway or the phosphatidylethanolamine...