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Skip to Search Results- 2Optical Tweezers
- 1Biophysics
- 1Conformational Plasticity
- 1Contour Length
- 1Force-extension curve
- 1Frameshift Efficiency
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Force spectroscopy of the frameshift signal from West Nile virus reveals multiple folding pathways and structural heterogeneity
DownloadSpring 2019
Programmed ribosomal frameshifting (PRF) represents an important mechanism for translational genetic recoding, especially in viruses. The components of a PRF stimulator have been well characterized, though accounting for the variation in the frameshift stimulating efficiency has thus far been...
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Fall 2014
The structural dynamics of proteins and nucleic acids play a vital role in biochemical reactions. We employed novel optical tweezers to study the programmed -1 ribosomal frameshifting, where the conformational plasticity of a SARS pseudoknot with a bound ligand is shown to be correlated to the...