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Fall 2021
Primary Biliary Cholangitis (PBC) is a complex cholestatic liver disorder with both environmental and genetic factors that contribute to disease. While the etiology remains poorly understood, our lab continues to characterize the role of a human betaretrovirus (HBRV) in the disease process. Based...
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Understanding Heart Failure in Patients with Dilated Cardiomyopathy: A Direct Tissue Analysis from Explanted Human Hearts
DownloadFall 2022
Background Chronic heart failure (HF) remains a rising global epidemic that affects both adults and children population. The causes of HF are heterogeneous, and syndromes are often complicated by concomitant disorders such as iron deficiency (ID) and diabetes. Comorbidities not only complicate...
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Understanding host-microbiome interactions and influence on STEC colonization in cattle using integrated omics
DownloadFall 2023
Shiga toxin producing Escherichia coli (STEC) is the major foodborne pathogen in humans with Shiga toxin 1 (stx1) and 2 (stx2) being the main virulence factors. Cattle are the major reservoir of STEC with those shedding >104 CFU/g STEC being defined as super shedders (SS). The rectal anal...