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- 1Baker, Perrin
- 1Clarke, Anthony J.
- 1Codee, Jeroen D. C.
- 1Dawson, Karen
- 1Glaves, John Paul J
- 1Howell, P. Lynne
Cryo-electron microscopy of SERCA interacting with oligomeric phospholamban and oligomeric sarcolipinDownload
In 2007, heart disease was the second leading cause of death in Canadians. In heart muscle cells, calcium (Ca2+) is released from the sarcoplasmic reticulum (SR) during contraction and must be replenished for relaxation to occur. Three proteins restore Ca2+ to the SR following contraction: the...
P. aeruginosa SGNH hydrolase-like proteins AlgJ and AlgX have similar topology but separate and distinct roles in alginate acetylationDownload
Howell, P. Lynne, Klassen, John S., Robinson, Howard, Kitova, Elena N., Dawson, Karen, Clarke, Anthony J., Little, Dustin J., Walvoort, Marthe T., Weadge, Joel T., Codee, Jeroen D. C., Baker, Perrin, Whitney, John C., Ohman, Dennis E., Ricer, Tyler, Moynihan, Patrick J.
The O-acetylation of polysaccharides is a common modification used by pathogenic organisms to protect against external forces. Pseudomonas aeruginosa secretes the anionic, O-acetylated exopolysaccharide alginate during chronic infection in the lungs of cystic fibrosis patients to form the major...
Synthesis and Properties of Graphyne Model Compounds and an Electrochemical Study of Substituted PentacenesDownload
The work described in this thesis focuses on two central topics: (1) the synthesis of carbon-rich macrocycles as model compounds of the carbon allotrope graphyne and the study of their electronic properties, and (2) the electrochemical investigation of the properties of substituted pentacene...