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- 8Myocardial Infarction
- 2Angina, Unstable
- 2Cardiac Troponin
- 2Heparin, Low-Molecular-Weight
Research is crucial for the development of treatment guidelines. Informed consent is an essential component to ensure the ethical integrity of research. An ideal informed consent should meet three requirements; disclosure of adequate information about the study, subjects understand the...
Background: The serum troponin assay is the biochemical gold standard for detecting myocardial infarction (MI). A major diagnostic issue is that some believe troponin levels can rise with reversible injury, in the absence of radiologically detectable infarct. Hypothesis: Because cell death...
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide, while ischemic heart disease (IHD) dominates the cause of CVD mortality. Following myocardial infarction (MI), the heart experiences a series of structural and functional changes, termed post-infarction...
Temporal Trends in In-Hospital Bleeding and Transfusion in a Contemporary Canadian ST Elevation Myocardial Infarction Patient PopulationDownload
Background: Although ST-elevation myocardial infarction (STEMI) management has evolved substantially over the last decade, its impact on bleeding and transfusion rates are largely unknown in a ‘real-world’ Canadian population. Using a large Canadian population health database, we evaluated the...
Ischemic cardiomyopathy remains the primary cause of heart failure worldwide. A disintegrin and metalloproteinases (ADAMs) are a family of membrane-bound proteases with diverse functions. ADAM15 is expressed in the myocardium and is involved in mechanisms associated with ischemic heart disease...
Troponin degradation products: more specific marker for myocardial infarction
Introduction Myocardial infarction (MI) is the death of cardiac muscle in the setting of severe ischemia (lack of oxygen and nutrient supply). Assay of serum troponin I (TnI) is the biochemical gold standard for detecting MI. With the development of high sensitivity assays, TnI is being detected...