Search
Skip to Search Results- 2Schopflocher, D. P.
- 2Svenson, L. W.
- 1Adegoke, Adeolu
- 1Baxter, G.
- 1Benson, Curtis A
- 1Bording-Jorgensen, M.
- 14Graduate and Postdoctoral Studies (GPS), Faculty of
- 14Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 3Nursing, Faculty of
- 2Nursing, Faculty of/Health Systems
- 1Nursing, Faculty of/Chronicity
- 1Medicine and Dentistry, Faculty of
-
Measuring proteomic changes associated with viral infections and neurodegenerative diseases using mass spectrometry
DownloadFall 2023
Viral infection and the resultant cellular stress can trigger significant changes to the cellular host proteome. Viral proteases essential to viral replication have been shown to cleave human host protein substrates as a mechanism of immune response evasion. The severe acute respiratory syndrome...
-
Pain and analgesia in experimental autoimmune encephalomyelitis: Contribution of the central nucleus of the amygdala
DownloadSpring 2021
Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation, degeneration and demyelinating lesions within the central nervous system. Chronic pain is a highly prevalent symptom associated with MS, affecting 50-80% of patients over the course of their disease....
-
2007
Warren, S. A., Yiannakoulias, N., Svenson, L. W., Schopflocher, D. P.
Our objective is to examine how persons diagnosed with Multiple Sclerosis (MS) and Parkinson's disease (PD) change residence following disease onset. We hypothesize that persons choose to change residence (locally or regionally) in different ways depending on whether or not they have been...
-
2007
Warren, K. G., Patten, S. B., Schopflocher, D. P., Metz, L. M., Warren, S., Svenson, L. W.
BACKGROUND: Multiple Sclerosis (MS) is reported to be uncommon among North American aboriginals despite frequent intermarriage with people of European ancestry, but few population-based studies have been conducted. The purpose of this study was to determine the prevalence of MS among First...
-
Promoting Activity Behaviour in Adults with Multiple Sclerosis: Feasibility, Preliminary Efficacy and Evaluation of Activity Measurement Tools
DownloadFall 2021
Background: Multiple sclerosis (MS) is the largest cause of non-traumatic neurological disability in young adults. Canada has one of the highest rates of MS in the world, with nearly 1 in every 385 Canadians living with the disease. People with MS deal with a broad range of symptoms including...
-
Spring 2023
Recent thymic emigrants (RTE) are newly generated T cells that have just been exported to the periphery, where they continue their maturation to become mature T cells. RTE have only undergone central tolerance in the thymus but not yet undergone peripheral tolerance. As such, it is imperative...
-
Sex Differences in Central Nervous System Plasticity and Pain in Experimental Autoimmune Encephalomyelitis
DownloadSpring 2019
Multiple sclerosis (MS) is a neurodegenerative autoimmune disease with many known structural and functional changes in the central nervous system (CNS). A well-recognized, but poorly understood, complication of MS is chronic pain. Little is known regarding the influence of sex on the development...
-
Spring 2017
MS is a chronic demyelinating disease of the CNS that presents with debilitating symptoms in the later stages of disease progression and therefore a high demand for targeted disease-modifying treatments exists. In order to create effective treatments the causalities between the symptoms and...