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Magnetic resonance imaging is an essential tool for assessing soft tissues. The desire for increased signal-to-noise and improved tissue contrast has spurred development of imaging systems operating at magnetic fields exceeding 3.0 Tesla (T). Unfortunately, traditional imaging methods are of...
An Investigation of Early Relapsing-Remitting Multiple Sclerosis Patients using Diffusion Tensor Imaging and SpectroscopyDownload
Hazlin Zaini, Zhang Chen, Min Liu, Fabrizio Giuliani, Chris Hanstock, Christian Beaulieu. Altered white matter connectivity between early Relapsing-Remitting Multiple Sclerosis patients, Abstract # 3610. Proceedings of the International Society for Magnetic Resonance in Medicine, 21st Annual...
Cerebrospinal fluid in a small cohort of patients with multiple sclerosis was generally free of microbial DNADownload
Multiple sclerosis (MS) is a common cause of non-traumatic neurologic disability with high incidence in many developed countries. Although the etiology of the disease remains elusive, it is thought to entail genetic and environmental causes, and microbial pathogens have also been envisioned as...
Cognitive deficits affect approximately 50% of multiple sclerosis (MS) patients and are associated with disease-related neurodegeneration. Prior MS-studies found decision making impairments uncorrelated with patients’ cognitive functions. Brain correlates of decision making in MS have not been...
Evidence-based medicine (EBM) is, simply, the conscientious and judicious use of medical research (“evidence”) in clinical practice (Sackett et al. 2000:1). EBM emerged as a solution to various identified uncertainties in clinical practice as a programme for intervention at the level of...
This study describes the experiences of four groups of healthcare providers who facilitate exercise interventions for people with multiple sclerosis (MS)-related fatigue. Fatigue is a complex symptom frequently experienced by people with MS, yet it is poorly understood by clinicians and clinical...
Investigation of gradient echo MRI for blood vessel imaging and susceptibility-weighted imaging in the human brainDownload
Despite the vast myriad of applications and the long way it has come, MRI is still a relatively new field of knowledge with much prospect for more advancement and expansion. This work is mainly concerned with two gradient echo imaging methods which are directly or indirectly related to blood...
Our objective is to examine how persons diagnosed with Multiple Sclerosis (MS) and Parkinson's disease (PD) change residence following disease onset. We hypothesize that persons choose to change residence (locally or regionally) in different ways depending on whether or not they have been...
BACKGROUND: Multiple Sclerosis (MS) is reported to be uncommon among North American aboriginals despite frequent intermarriage with people of European ancestry, but few population-based studies have been conducted. The purpose of this study was to determine the prevalence of MS among First...