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- 2Schopflocher, D. P.
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Magnetic resonance imaging is an essential tool for assessing soft tissues. The desire for increased signal-to-noise and improved tissue contrast has spurred development of imaging systems operating at magnetic fields exceeding 3.0 Tesla (T). Unfortunately, traditional imaging methods are of...
An Investigation of Early Relapsing-Remitting Multiple Sclerosis Patients using Diffusion Tensor Imaging and SpectroscopyDownload
Hazlin Zaini, Zhang Chen, Min Liu, Fabrizio Giuliani, Chris Hanstock, Christian Beaulieu. Altered white matter connectivity between early Relapsing-Remitting Multiple Sclerosis patients, Abstract # 3610. Proceedings of the International Society for Magnetic Resonance in Medicine, 21st Annual...
Central nervous system plasticity associated with pain in a mouse model of multiple sclerosis, and the antinociceptive effects of the antidepressant phenelzineDownload
Multiple sclerosis (MS) is a chronic, progressive disease that involves neuroinflammation, demyelination, and neurodegeneration within the central nervous system (CNS). While loss of motor function and paralysis are considered the primary clinical consequences of MS, the disease is also...
Cerebrospinal fluid in a small cohort of patients with multiple sclerosis was generally free of microbial DNADownload
Multiple sclerosis (MS) is a common cause of non-traumatic neurologic disability with high incidence in many developed countries. Although the etiology of the disease remains elusive, it is thought to entail genetic and environmental causes, and microbial pathogens have also been envisioned as...
Cognitive deficits affect approximately 50% of multiple sclerosis (MS) patients and are associated with disease-related neurodegeneration. Prior MS-studies found decision making impairments uncorrelated with patients’ cognitive functions. Brain correlates of decision making in MS have not been...
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system characterized by neurodegeneration, inflammation and demyelination. Symptoms of multiple sclerosis not only include motor deficits, but also secondary symptoms of pain, depression and anxiety. The purpose of...
Evidence-based medicine (EBM) is, simply, the conscientious and judicious use of medical research (“evidence”) in clinical practice (Sackett et al. 2000:1). EBM emerged as a solution to various identified uncertainties in clinical practice as a programme for intervention at the level of...
This study describes the experiences of four groups of healthcare providers who facilitate exercise interventions for people with multiple sclerosis (MS)-related fatigue. Fatigue is a complex symptom frequently experienced by people with MS, yet it is poorly understood by clinicians and clinical...
Investigation of gradient echo MRI for blood vessel imaging and susceptibility-weighted imaging in the human brainDownload
Despite the vast myriad of applications and the long way it has come, MRI is still a relatively new field of knowledge with much prospect for more advancement and expansion. This work is mainly concerned with two gradient echo imaging methods which are directly or indirectly related to blood...