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Skip to Search Results- 1Bahitham, Wesam
- 1Bamforth, Fiona
- 1Chan, Alicia
- 1Chan, Catherine B.
- 1Holloway, Graham P.
- 1Liao, Xiaoping
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2012
Wan, Zhongxiao, MacDonald, Tara, Wright, David C., Holloway, Graham P., Chan, Catherine B., Perry, Christopher G.
Background Adipose tissue mitochondria have been implicated as key mediators of systemic metabolism. We have shown that IL-6 activates AMPK, a mediator of mitochondrial biogenesis, in adipose tissue; however, IL-6−/− mice fed a high fat diet have been reported to develop insulin resistance. These...
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2014
Bamforth, Fiona, Stothard, Paul, Peng, Fred, Sergi, Consolato, Chan, Alicia, Bahitham, Wesam, Stone, Bradley, Mason, Andrew, Liao, Xiaoping
Cholangiocellular carcinoma (CCA) of the liver was the target of more interest, recently, due mainly to its increased incidence and possible association to new environmental factors. Somatic mitochondrial DNA (mtDNA) mutations have been found in several cancers. Some of these malignancies contain...