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- 2Graduate Studies and Research, Faculty of
- 2Graduate Studies and Research, Faculty of/Theses and Dissertations
- 1Agricultural, Food and Nutritional Science, Department of
- 1Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 1Roy Berg Kinsella Research Ranch
- 1Roy Berg Kinsella Research Ranch/Journal Articles (Kinsella Ranch)
Association of a single nucleotide polymorphism in the bovine leptin gene with feed intake, feed efficiency, growth, feeding behaviour, carcass quality and body compositionDownload
Leptin is a 16-kDa-hormone product of the obese gene synthesized and expressed predominantly by adipose tissues, which has been shown to play major roles in the regulation of body weight, feed intake, energy balance, fertility, and immune system functions. We report an investigation into the...
Cardiomyocyte antihypertrophic effect of adipocyte tissue conditioned medium from rats and its abrogation by obesity is mediated by the leptin to adiponectin ratioDownload
White adipocytes are known to function as endocrine organs by secreting a plethora of bioactive adipokines which can regulate cardiac function including the development of hypertrophy. We determined whether adipose tissue conditioned medium (ATCM) generated from the epididymal regions of normal...
Characterizing the Mesolimbic Dopamine Reward Pathway in a Magel2-null Mouse, a Model of Prader-Willi SyndromeDownload
Prader-Willi Syndrome (PWS) is a genetic disorder characterized by extreme hyperphagia that can lead to severe obesity. The abnormal motivation to eat in PWS suggests a disruption in the hedonic feeding pathway, which is feeding based on reward as opposed to physiological need. Hedonic feeding is...
An individual’s body weight is tightly regulated by balancing food intake with energy expenditure. This is accomplished in part by secretion of the hormone leptin by adipocytes, an excess of which signals to reduce appetite and increase activity through action in the hypothalamic region of the...